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High-affinity SOAT1 ligands remodeled cholesterol metabolism program to inhibit tumor growth

BACKGROUND: Although cholesterol metabolism is a common pathway for the development of antitumor drugs, there are no specific targets and drugs for clinical use. Here, based on our previous study of sterol O-acyltransferase 1 (SOAT1) in hepatocelluar carcinoma, we sought to screen an effective targe...

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Detalles Bibliográficos
Autores principales:	Wang, Zhihua, Wang, Miaomiao, Zhang, Mengxin, Xu, Kaikun, Zhang, Xinshuai, Xie, Yi, Zhang, Yiming, Chang, Cheng, Li, Xiaolu, Sun, Aihua, He, Fuchu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361549/ https://www.ncbi.nlm.nih.gov/pubmed/35941608 http://dx.doi.org/10.1186/s12916-022-02436-8

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