STAT3-mediated upregulation of LINC00520 contributed to temozolomide chemoresistance in glioblastoma by interacting with RNA-binding protein LIN28B

A considerable number of glioblastoma (GBM) patients developed drug resistance to Temozolomide (TMZ) during chemotherapy, resulting in therapeutic failure and tumor recurrence. However, the exact mechanism of TMZ chemoresistance in GBM is still poorly clarified. As a novel identified lncRNA, LINC005...

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Detalles Bibliográficos
Autores principales: Yuan, Shuai, Yan, Qi, Zhao, Zhi-yong, Zhang, Jing-long, Zhang, He, Yin, Hang, Yuan, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361558/
https://www.ncbi.nlm.nih.gov/pubmed/35945579
http://dx.doi.org/10.1186/s12935-022-02659-y

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