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The upregulation of stromal antigen 3 expression suppresses the phenotypic hallmarks of hepatocellular carcinoma through the Smad3-CDK4/CDK6-cyclin D1 and CXCR4/RhoA pathways

BACKGROUND: The stromal antigen 3 (STAG3) gene encodes an adhesion complex subunit that can regulate sister chromatid cohesion during cell division. Chromosome instability caused by STAG3 gene mutation may potentially promote tumor progression, but the effect of STAG3 on hepatocellular carcinoma (HC...

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Detalles Bibliográficos
Autores principales: Zhao, Menglin, Wang, Yanyan, Zhang, Yue, Li, Xinwei, Mi, Jiaqi, Wang, Qiang, Geng, Zhijun, Zuo, Lugen, Song, Xue, Ge, Sitang, Zhang, Zining, Tang, Mingyue, Li, Huiyuan, Wang, Zishu, Jiang, Chenchen, Su, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361574/
https://www.ncbi.nlm.nih.gov/pubmed/35941537
http://dx.doi.org/10.1186/s12876-022-02400-z