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Incidental discovery of a Hodgkin lymphoma synchronous to a papillary thyroid carcinoma

Papillary thyroid carcinoma is the most common type of thyroid cancer and accounts for almost 89.4% of all thyroid carcinomas. Hodgkin lymphoma is a heterogeneous group of neoplasms and represents 10% of lymphomas. These two cancers do not share the same risk factors. Some studies have reported the...

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Autores principales: Ben Thayer, Maissa, Khanchel, Fatma, Helal, Imen, Chiboub, Dorra, Ben Lazreg, Khouloud, Hedhli, Raweh, Ben Brahim, Ehsen, Jouini, Raja, Cheddli‐Debbich, Aschraf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361809/
https://www.ncbi.nlm.nih.gov/pubmed/35957786
http://dx.doi.org/10.1002/ccr3.6246
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author Ben Thayer, Maissa
Khanchel, Fatma
Helal, Imen
Chiboub, Dorra
Ben Lazreg, Khouloud
Hedhli, Raweh
Ben Brahim, Ehsen
Jouini, Raja
Cheddli‐Debbich, Aschraf
author_facet Ben Thayer, Maissa
Khanchel, Fatma
Helal, Imen
Chiboub, Dorra
Ben Lazreg, Khouloud
Hedhli, Raweh
Ben Brahim, Ehsen
Jouini, Raja
Cheddli‐Debbich, Aschraf
author_sort Ben Thayer, Maissa
collection PubMed
description Papillary thyroid carcinoma is the most common type of thyroid cancer and accounts for almost 89.4% of all thyroid carcinomas. Hodgkin lymphoma is a heterogeneous group of neoplasms and represents 10% of lymphomas. These two cancers do not share the same risk factors. Some studies have reported the association of thyroid papillary carcinoma with lymphomas, mainly Hodgkin's lymphoma, treated with radiotherapy. However, to our knowledge less than 10 cases have illustrated synchronous papillary thyroid carcinoma and Hodgkin lymphoma with no history of radiotherapy. We present the case of a 49‐year‐old female patient, with no history of past exposure to radiation, who was incidentally diagnosed with Hodgkin lymphoma during the work up for papillary thyroid carcinoma. Our patient had total thyroïdectomy with cervical lymphadenectomy. The histopathologic examination concluded to a papillary thyroid carcinoma of classical variant. And the lymph node dissection enabled us to diagnose not only papillary thyroid carcinoma's lymph node metastasis, but also Hodgkin Lymphoma. This discovery of the Hodgkin lymphoma was totally incidental. The discovery of synchronous tumors in patients with papillary thyroid carcinoma has been reported in the literature. However, the diagnosis of Hodgkin through lymph node dissection for papillary thyroid carcinoma is extremely rare. This underlines the singularity and the importance of our case. The synchronous papillary thyroid carcinoma and Hodgkin lymphoma is a rare condition, which may pose significant diagnostic and treatment dilemmas. To date, there is no standardized approach due to lack of experience. The molecular mechanisms of this link are poorly understood and yet remain to be elucidated.
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spelling pubmed-93618092022-08-10 Incidental discovery of a Hodgkin lymphoma synchronous to a papillary thyroid carcinoma Ben Thayer, Maissa Khanchel, Fatma Helal, Imen Chiboub, Dorra Ben Lazreg, Khouloud Hedhli, Raweh Ben Brahim, Ehsen Jouini, Raja Cheddli‐Debbich, Aschraf Clin Case Rep Case Report Papillary thyroid carcinoma is the most common type of thyroid cancer and accounts for almost 89.4% of all thyroid carcinomas. Hodgkin lymphoma is a heterogeneous group of neoplasms and represents 10% of lymphomas. These two cancers do not share the same risk factors. Some studies have reported the association of thyroid papillary carcinoma with lymphomas, mainly Hodgkin's lymphoma, treated with radiotherapy. However, to our knowledge less than 10 cases have illustrated synchronous papillary thyroid carcinoma and Hodgkin lymphoma with no history of radiotherapy. We present the case of a 49‐year‐old female patient, with no history of past exposure to radiation, who was incidentally diagnosed with Hodgkin lymphoma during the work up for papillary thyroid carcinoma. Our patient had total thyroïdectomy with cervical lymphadenectomy. The histopathologic examination concluded to a papillary thyroid carcinoma of classical variant. And the lymph node dissection enabled us to diagnose not only papillary thyroid carcinoma's lymph node metastasis, but also Hodgkin Lymphoma. This discovery of the Hodgkin lymphoma was totally incidental. The discovery of synchronous tumors in patients with papillary thyroid carcinoma has been reported in the literature. However, the diagnosis of Hodgkin through lymph node dissection for papillary thyroid carcinoma is extremely rare. This underlines the singularity and the importance of our case. The synchronous papillary thyroid carcinoma and Hodgkin lymphoma is a rare condition, which may pose significant diagnostic and treatment dilemmas. To date, there is no standardized approach due to lack of experience. The molecular mechanisms of this link are poorly understood and yet remain to be elucidated. John Wiley and Sons Inc. 2022-08-09 /pmc/articles/PMC9361809/ /pubmed/35957786 http://dx.doi.org/10.1002/ccr3.6246 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Ben Thayer, Maissa
Khanchel, Fatma
Helal, Imen
Chiboub, Dorra
Ben Lazreg, Khouloud
Hedhli, Raweh
Ben Brahim, Ehsen
Jouini, Raja
Cheddli‐Debbich, Aschraf
Incidental discovery of a Hodgkin lymphoma synchronous to a papillary thyroid carcinoma
title Incidental discovery of a Hodgkin lymphoma synchronous to a papillary thyroid carcinoma
title_full Incidental discovery of a Hodgkin lymphoma synchronous to a papillary thyroid carcinoma
title_fullStr Incidental discovery of a Hodgkin lymphoma synchronous to a papillary thyroid carcinoma
title_full_unstemmed Incidental discovery of a Hodgkin lymphoma synchronous to a papillary thyroid carcinoma
title_short Incidental discovery of a Hodgkin lymphoma synchronous to a papillary thyroid carcinoma
title_sort incidental discovery of a hodgkin lymphoma synchronous to a papillary thyroid carcinoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361809/
https://www.ncbi.nlm.nih.gov/pubmed/35957786
http://dx.doi.org/10.1002/ccr3.6246
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