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Biosynthesis of Aurodox, a Type III Secretion System Inhibitor from Streptomyces goldiniensis

The global increase in antimicrobial-resistant infections means that there is a need to develop new antimicrobial molecules and strategies to combat the issue. Aurodox is a linear polyketide natural product that is produced by Streptomyces goldiniensis, yet little is known about aurodox biosynthesis...

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Detalles Bibliográficos
Autores principales: McHugh, Rebecca E., Munnoch, John T., Braes, Robyn E., McKean, Iain J. W., Giard, Josephine, Taladriz-Sender, Andrea, Peschke, Frederik, Burley, Glenn A., Roe, Andrew J., Hoskisson, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361827/
https://www.ncbi.nlm.nih.gov/pubmed/35867559
http://dx.doi.org/10.1128/aem.00692-22