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Single-cell transcriptomics reveals shared immunosuppressive landscapes of mouse and human neuroblastoma

BACKGROUND: High-risk neuroblastoma is a pediatric cancer with still a dismal prognosis, despite multimodal and intensive therapies. Tumor microenvironment represents a key component of the tumor ecosystem the complexity of which has to be accurately understood to define selective targeting opportun...

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Detalles Bibliográficos
Autores principales: Costa, Ana, Thirant, Cécile, Kramdi, Amira, Pierre-Eugène, Cécile, Louis-Brennetot, Caroline, Blanchard, Orphée, Surdez, Didier, Gruel, Nadege, Lapouble, Eve, Pierron, Gaëlle, Sitbon, Deborah, Brisse, Hervé, Gauthier, Arnaud, Fréneaux, Paul, Bohec, Mylène, Raynal, Virginie, Baulande, Sylvain, Leclere, Renaud, Champenois, Gabriel, Nicolas, Andre, Meseure, Didier, Bellini, Angela, Marabelle, Aurelien, Geoerger, Birgit, Mechta-Grigoriou, Fatima, Schleiermacher, Gudrun, Menger, Laurie, Delattre, Olivier, Janoueix-Lerosey, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362821/
https://www.ncbi.nlm.nih.gov/pubmed/36054452
http://dx.doi.org/10.1136/jitc-2022-004807