Cargando…
Single-cell transcriptomics reveals shared immunosuppressive landscapes of mouse and human neuroblastoma
BACKGROUND: High-risk neuroblastoma is a pediatric cancer with still a dismal prognosis, despite multimodal and intensive therapies. Tumor microenvironment represents a key component of the tumor ecosystem the complexity of which has to be accurately understood to define selective targeting opportun...
Autores principales: | Costa, Ana, Thirant, Cécile, Kramdi, Amira, Pierre-Eugène, Cécile, Louis-Brennetot, Caroline, Blanchard, Orphée, Surdez, Didier, Gruel, Nadege, Lapouble, Eve, Pierron, Gaëlle, Sitbon, Deborah, Brisse, Hervé, Gauthier, Arnaud, Fréneaux, Paul, Bohec, Mylène, Raynal, Virginie, Baulande, Sylvain, Leclere, Renaud, Champenois, Gabriel, Nicolas, Andre, Meseure, Didier, Bellini, Angela, Marabelle, Aurelien, Geoerger, Birgit, Mechta-Grigoriou, Fatima, Schleiermacher, Gudrun, Menger, Laurie, Delattre, Olivier, Janoueix-Lerosey, Isabelle |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362821/ https://www.ncbi.nlm.nih.gov/pubmed/36054452 http://dx.doi.org/10.1136/jitc-2022-004807 |
Ejemplares similares
-
Reversible transitions between noradrenergic and mesenchymal tumor identities define cell plasticity in neuroblastoma
por: Thirant, Cécile, et al.
Publicado: (2023) -
BET and CDK Inhibition Reveal Differences in the Proliferation Control of Sympathetic Ganglion Neuroblasts and Adrenal Chromaffin Cells
por: Sriha, Jessica, et al.
Publicado: (2022) -
Activated ALK signals through the ERK–ETV5–RET pathway to drive neuroblastoma oncogenesis
por: Lopez-Delisle, Lucille, et al.
Publicado: (2018) -
ALK mutation dynamics and clonal evolution in a neuroblastoma model exhibiting two ALK mutations
por: Durand, Simon, et al.
Publicado: (2019) -
Radiogenomics of neuroblastomas: Relationships between imaging phenotypes, tumor genomic profile and survival
por: Brisse, Hervé J., et al.
Publicado: (2017)