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Adrenergic signaling controls early transcriptional programs during CD8(+) T cell responses to viral infection
Norepinephrine is a key sympathetic neurotransmitter, which acts to suppress CD8 (+) T cell cytokine secretion and lytic activity by signaling through the β2-adrenergic receptor (ADRB2). Although ADRB2 signaling is considered generally immunosuppressive, its role in regulating the differentiation of...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362915/ https://www.ncbi.nlm.nih.gov/pubmed/35944008 http://dx.doi.org/10.1371/journal.pone.0272017 |