A suite of PCR-LwCas13a assays for detection and genotyping of Treponema pallidum in clinical samples

The performance of commonly used assays for diagnosis of syphilis varies considerably depending on stage of infection and sample type. In response to the need for improved syphilis diagnostics, we develop assays that pair PCR pre-amplification of the tpp47 gene of Treponema pallidum subsp. pallidum...

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Detalles Bibliográficos
Autores principales: Chen, Wentao, Luo, Hao, Zeng, Lihong, Pan, Yuying, Parr, Jonathan B., Jiang, Yinbo, Cunningham, Clark H., Hawley, Kelly L., Radolf, Justin D., Ke, Wujian, Ou, Jiangli, Yang, Jianjiang, Yang, Bin, Zheng, Heping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362966/
https://www.ncbi.nlm.nih.gov/pubmed/35945210
http://dx.doi.org/10.1038/s41467-022-32250-y

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