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The JAK inhibitor ruxolitinib abrogates immune hepatitis instigated by concanavalin A in mice
Therapeutics that impair the innate immune responses of the liver during the inflammatory cytokine storm like that occurring in COVID-19 are greatly needed. Much interest is currently directed toward Janus kinase (JAK) inhibitors as potential candidates to mitigate this life-threatening complication...
Autores principales: | Shaker, Mohamed E., Hendawy, Omnia M., El-Mesery, Mohamed, Hazem, Sara H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363025/ https://www.ncbi.nlm.nih.gov/pubmed/34952468 http://dx.doi.org/10.1016/j.intimp.2021.108463 |
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