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In vitro assessment of the potential for dolutegravir to affect hepatic clearance of levonorgestrel

OBJECTIVES: The World Health Organization recommends that all countries adopt dolutegravir-based antiretroviral therapy as the preferred regimen for all individuals living with HIV. Levonorgestrel is a commonly used hormonal contraceptive, which undergoes drug–drug interactions with some antiretrovi...

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Detalles Bibliográficos
Autores principales: Roberts, Owain, Kinvig, Hannah, Owen, Andrew, Lamorde, Mohammed, Siccardi, Marco, Scarsi, Kimberly K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363158/
https://www.ncbi.nlm.nih.gov/pubmed/34328253
http://dx.doi.org/10.1111/hiv.13136