Cargando…
Stem Cell Therapy and Innate Lymphoid Cells
Innate lymphoid cells have the capability to communicate with other immune cell types to coordinate the immune system functioning during homeostasis and inflammation. However, these cells behave differently at the functional level, unlike T cells, these cells do not need antigen receptors for activa...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363162/ https://www.ncbi.nlm.nih.gov/pubmed/35958032 http://dx.doi.org/10.1155/2022/3530520 |
_version_ | 1784764867211689984 |
---|---|
author | Verma, Divya Verma, Mukesh Mishra, Rangnath |
author_facet | Verma, Divya Verma, Mukesh Mishra, Rangnath |
author_sort | Verma, Divya |
collection | PubMed |
description | Innate lymphoid cells have the capability to communicate with other immune cell types to coordinate the immune system functioning during homeostasis and inflammation. However, these cells behave differently at the functional level, unlike T cells, these cells do not need antigen receptors for activation because they are activated by the interaction of their receptor ligation. In hematopoietic stem cell transplantation (HSCT), T cells and NK cells have been extensively studied but very few studies are available on ILCs. In this review, an attempt has been made to provide current information related to NK and ILCs cell-based stem cell therapies and role of the stem cells in the regulation of ILCs as well. Also, the latest information on the differentiation of NK cells and ILCs from CD34+ hematopoietic stem cells is covered in the article. |
format | Online Article Text |
id | pubmed-9363162 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-93631622022-08-10 Stem Cell Therapy and Innate Lymphoid Cells Verma, Divya Verma, Mukesh Mishra, Rangnath Stem Cells Int Review Article Innate lymphoid cells have the capability to communicate with other immune cell types to coordinate the immune system functioning during homeostasis and inflammation. However, these cells behave differently at the functional level, unlike T cells, these cells do not need antigen receptors for activation because they are activated by the interaction of their receptor ligation. In hematopoietic stem cell transplantation (HSCT), T cells and NK cells have been extensively studied but very few studies are available on ILCs. In this review, an attempt has been made to provide current information related to NK and ILCs cell-based stem cell therapies and role of the stem cells in the regulation of ILCs as well. Also, the latest information on the differentiation of NK cells and ILCs from CD34+ hematopoietic stem cells is covered in the article. Hindawi 2022-08-02 /pmc/articles/PMC9363162/ /pubmed/35958032 http://dx.doi.org/10.1155/2022/3530520 Text en Copyright © 2022 Divya Verma et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Verma, Divya Verma, Mukesh Mishra, Rangnath Stem Cell Therapy and Innate Lymphoid Cells |
title | Stem Cell Therapy and Innate Lymphoid Cells |
title_full | Stem Cell Therapy and Innate Lymphoid Cells |
title_fullStr | Stem Cell Therapy and Innate Lymphoid Cells |
title_full_unstemmed | Stem Cell Therapy and Innate Lymphoid Cells |
title_short | Stem Cell Therapy and Innate Lymphoid Cells |
title_sort | stem cell therapy and innate lymphoid cells |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363162/ https://www.ncbi.nlm.nih.gov/pubmed/35958032 http://dx.doi.org/10.1155/2022/3530520 |
work_keys_str_mv | AT vermadivya stemcelltherapyandinnatelymphoidcells AT vermamukesh stemcelltherapyandinnatelymphoidcells AT mishrarangnath stemcelltherapyandinnatelymphoidcells |