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Preclinical Pharmacokinetics, Biodistribution, and Acute Toxicity Evaluation of Caerin 1.9 Peptide in Sprague Dawley Rats
Caerin 1.9 is a natural peptide derived from the skin secretions of the Australian tree frog (Litoria) with broad-spectrum antimicrobial and anticancer bioactivity. It improves the efficacy of a therapeutic vaccine and immune checkpoint inhibitor therapy when injected intratumorally and inhibits TC-...
Autores principales: | Yang, Xiaodan, Li, Junjie, Chen, Shu, Xiao, Liyin, Cao, Dongmin, Wu, Xiaolian, Li, Hejie, Ni, Guoying, Wang, Tianfang, Chen, Guoqiang, Liu, Xiaosong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363195/ https://www.ncbi.nlm.nih.gov/pubmed/35958922 http://dx.doi.org/10.1155/2022/9869293 |
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