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Age at onset as stratifier in idiopathic Parkinson’s disease – effect of ageing and polygenic risk score on clinical phenotypes

Several phenotypic differences observed in Parkinson’s disease (PD) patients have been linked to age at onset (AAO). We endeavoured to find out whether these differences are due to the ageing process itself by using a combined dataset of idiopathic PD (n = 430) and healthy controls (HC; n = 556) exc...

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Detalles Bibliográficos
Autores principales:	Pavelka, L., Rauschenberger, A., Landoulsi, Z., Pachchek, S., May, P., Glaab, E., Krüger, R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363416/ https://www.ncbi.nlm.nih.gov/pubmed/35945230 http://dx.doi.org/10.1038/s41531-022-00342-7

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