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Human brain structural connectivity matrices–ready for modelling

The human brain represents a complex computational system, the function and structure of which may be measured using various neuroimaging techniques focusing on separate properties of the brain tissue and activity. We capture the organization of white matter fibers acquired by diffusion-weighted ima...

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Autores principales: Škoch, Antonín, Rehák Bučková, Barbora, Mareš, Jan, Tintěra, Jaroslav, Sanda, Pavel, Jajcay, Lucia, Horáček, Jiří, Španiel, Filip, Hlinka, Jaroslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363436/
https://www.ncbi.nlm.nih.gov/pubmed/35945231
http://dx.doi.org/10.1038/s41597-022-01596-9
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author Škoch, Antonín
Rehák Bučková, Barbora
Mareš, Jan
Tintěra, Jaroslav
Sanda, Pavel
Jajcay, Lucia
Horáček, Jiří
Španiel, Filip
Hlinka, Jaroslav
author_facet Škoch, Antonín
Rehák Bučková, Barbora
Mareš, Jan
Tintěra, Jaroslav
Sanda, Pavel
Jajcay, Lucia
Horáček, Jiří
Španiel, Filip
Hlinka, Jaroslav
author_sort Škoch, Antonín
collection PubMed
description The human brain represents a complex computational system, the function and structure of which may be measured using various neuroimaging techniques focusing on separate properties of the brain tissue and activity. We capture the organization of white matter fibers acquired by diffusion-weighted imaging using probabilistic diffusion tractography. By segmenting the results of tractography into larger anatomical units, it is possible to draw inferences about the structural relationships between these parts of the system. This pipeline results in a structural connectivity matrix, which contains an estimate of connection strength among all regions. However, raw data processing is complex, computationally intensive, and requires expert quality control, which may be discouraging for researchers with less experience in the field. We thus provide brain structural connectivity matrices in a form ready for modelling and analysis and thus usable by a wide community of scientists. The presented dataset contains brain structural connectivity matrices together with the underlying raw diffusion and structural data, as well as basic demographic data of 88 healthy subjects.
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spelling pubmed-93634362022-08-11 Human brain structural connectivity matrices–ready for modelling Škoch, Antonín Rehák Bučková, Barbora Mareš, Jan Tintěra, Jaroslav Sanda, Pavel Jajcay, Lucia Horáček, Jiří Španiel, Filip Hlinka, Jaroslav Sci Data Data Descriptor The human brain represents a complex computational system, the function and structure of which may be measured using various neuroimaging techniques focusing on separate properties of the brain tissue and activity. We capture the organization of white matter fibers acquired by diffusion-weighted imaging using probabilistic diffusion tractography. By segmenting the results of tractography into larger anatomical units, it is possible to draw inferences about the structural relationships between these parts of the system. This pipeline results in a structural connectivity matrix, which contains an estimate of connection strength among all regions. However, raw data processing is complex, computationally intensive, and requires expert quality control, which may be discouraging for researchers with less experience in the field. We thus provide brain structural connectivity matrices in a form ready for modelling and analysis and thus usable by a wide community of scientists. The presented dataset contains brain structural connectivity matrices together with the underlying raw diffusion and structural data, as well as basic demographic data of 88 healthy subjects. Nature Publishing Group UK 2022-08-09 /pmc/articles/PMC9363436/ /pubmed/35945231 http://dx.doi.org/10.1038/s41597-022-01596-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Data Descriptor
Škoch, Antonín
Rehák Bučková, Barbora
Mareš, Jan
Tintěra, Jaroslav
Sanda, Pavel
Jajcay, Lucia
Horáček, Jiří
Španiel, Filip
Hlinka, Jaroslav
Human brain structural connectivity matrices–ready for modelling
title Human brain structural connectivity matrices–ready for modelling
title_full Human brain structural connectivity matrices–ready for modelling
title_fullStr Human brain structural connectivity matrices–ready for modelling
title_full_unstemmed Human brain structural connectivity matrices–ready for modelling
title_short Human brain structural connectivity matrices–ready for modelling
title_sort human brain structural connectivity matrices–ready for modelling
topic Data Descriptor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363436/
https://www.ncbi.nlm.nih.gov/pubmed/35945231
http://dx.doi.org/10.1038/s41597-022-01596-9
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