New diterpenes from the marine sponge Spongionella sp. overcome drug resistance in prostate cancer by inhibition of P-glycoprotein

Spongian diterpenes are a group of marine natural compounds possessing various biological activities. However, their anticancer activity is still poorly studied and understood. We isolated six spongian diterpenes from the marine sponge Spongionella sp., including one new spongionellol A and five pre...

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Detalles Bibliográficos
Autores principales: Dyshlovoy, Sergey A., Shubina, Larisa K., Makarieva, Tatyana N., Hauschild, Jessica, Strewinsky, Nadja, Guzii, Alla G., Menshov, Alexander S., Popov, Roman S., Grebnev, Boris B., Busenbender, Tobias, Oh-Hohenhorst, Su Jung, Maurer, Tobias, Tilki, Derya, Graefen, Markus, Bokemeyer, Carsten, Stonik, Valentin A., von Amsberg, Gunhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363487/
https://www.ncbi.nlm.nih.gov/pubmed/35945234
http://dx.doi.org/10.1038/s41598-022-17447-x

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