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Transferability of genetic loci and polygenic scores for cardiometabolic traits in British Pakistani and Bangladeshi individuals

Individuals with South Asian ancestry have a higher risk of heart disease than other groups but have been largely excluded from genetic research. Using data from 22,000 British Pakistani and Bangladeshi individuals with linked electronic health records from the Genes & Health cohort, we conducte...

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Detalles Bibliográficos
Autores principales: Huang, Qin Qin, Sallah, Neneh, Dunca, Diana, Trivedi, Bhavi, Hunt, Karen A., Hodgson, Sam, Lambert, Samuel A., Arciero, Elena, Wright, John, Griffiths, Chris, Trembath, Richard C., Hemingway, Harry, Inouye, Michael, Finer, Sarah, van Heel, David A., Lumbers, R. Thomas, Martin, Hilary C., Kuchenbaecker, Karoline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363492/
https://www.ncbi.nlm.nih.gov/pubmed/35945198
http://dx.doi.org/10.1038/s41467-022-32095-5