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Therapeutic potential of an anti-CCR9 mAb evidenced in xenografts of human CCR9(+) tumors

Relapsed or refractory T acute lymphoblastic leukemia (T-ALL) still carries poor prognosis. Aiming to improve outcomes, the therapeutic potential of an anti-CCR9 monoclonal antibody (mAb 92R), targeting the human chemokine-receptor CCR9 is analyzed on orthotopic xenotransplants. 92R mAb treatment of...

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Detalles Bibliográficos
Autores principales:	Santamaria, Silvia, Delgado, Marisa, Botas, Marta, Castellano, Eva, Corraliza-Gorjon, Isabel, Lafuente, Paloma, Muñoz-Calleja, Cecilia, Toribio, Maria L., Kremer, Leonor, Garcia-Sanz, Jose A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363564/ https://www.ncbi.nlm.nih.gov/pubmed/35967322 http://dx.doi.org/10.3389/fimmu.2022.825635

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