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Protective role of Cav-1 in pneumolysin-induced endothelial barrier dysfunction

Pneumolysin (PLY) is a bacterial pore forming toxin and primary virulence factor of Streptococcus pneumonia, a major cause of pneumonia. PLY binds cholesterol-rich domains of the endothelial cell (EC) plasma membrane resulting in pore assembly and increased intracellular (IC) Ca(2+) levels that comp...

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Detalles Bibliográficos
Autores principales:	Batori, Robert K., Chen, Feng, Bordan, Zsuzsanna, Haigh, Stephen, Su, Yunchao, Verin, Alexander D., Barman, Scott A., Stepp, David W., Chakraborty, Trinad, Lucas, Rudolf, Fulton, David J. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363592/ https://www.ncbi.nlm.nih.gov/pubmed/35967431 http://dx.doi.org/10.3389/fimmu.2022.945656

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