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RNA induces unique tau strains and stabilizes Alzheimer’s disease seeds

Tau aggregation underlies neurodegenerative tauopathies, and transcellular propagation of tau assemblies of unique structure, i.e., strains, may underlie the diversity of these disorders. Polyanions have been reported to induce tau aggregation in vitro, but the precise trigger to convert tau from an...

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Detalles Bibliográficos
Autores principales:	Zwierzchowski-Zarate, Amy N., Mendoza-Oliva, Aydé, Kashmer, Omar M., Collazo-Lopez, Josue E., White, Charles L., Diamond, Marc I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364032/ https://www.ncbi.nlm.nih.gov/pubmed/35700826 http://dx.doi.org/10.1016/j.jbc.2022.102132

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