Efficacy of cancer-specific anti-podoplanin CAR-T cells and oncolytic herpes virus G47Δ combination therapy against glioblastoma

Glioblastoma is a devastating malignant brain tumor with a poor prognosis despite standard therapy. Podoplanin (PDPN), a type I transmembrane mucin-like glycoprotein that is overexpressed in various cancers, is a potential therapeutic target for the treatment of glioblastoma. We previously reported...

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Detalles Bibliográficos
Autores principales: Chalise, Lushun, Kato, Akira, Ohno, Masasuke, Maeda, Sachi, Yamamichi, Akane, Kuramitsu, Shunichiro, Shiina, Satoshi, Takahashi, Hiromi, Ozone, Sachiko, Yamaguchi, Junya, Kato, Yukinari, Rockenbach, Yumi, Natsume, Atsushi, Todo, Tomoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364057/
https://www.ncbi.nlm.nih.gov/pubmed/35991754
http://dx.doi.org/10.1016/j.omto.2022.07.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364057/
https://www.ncbi.nlm.nih.gov/pubmed/35991754
http://dx.doi.org/10.1016/j.omto.2022.07.006

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