Altereporenes A–E, five epoxy octa-hydronaphthalene polyketides produced by an endophytic fungus Alternaria sp. YUD20002

Five previously undescribed epoxy octa-hydronaphthalene polyketides, altereporenes A–E (1–5) were isolated from rice culture of the endophytic fungus Alternaria sp. YUD20002 derived from the tubers of Solanum tuberosum. Their structures were determined on the basis of comprehensive spectroscopic ana...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Dan-Dan, Duan, Hao-Jie, Xie, Fei, Xie, Tian-Peng, Zhang, Yan, Sun, Yue, Lu, Jian-Mei, Gao, Yu-Hong, Zhou, Hao, Ding, Zhong-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364171/
https://www.ncbi.nlm.nih.gov/pubmed/36043060
http://dx.doi.org/10.1039/d2ra03917f
_version_ 1784765091364732928
author Xia, Dan-Dan
Duan, Hao-Jie
Xie, Fei
Xie, Tian-Peng
Zhang, Yan
Sun, Yue
Lu, Jian-Mei
Gao, Yu-Hong
Zhou, Hao
Ding, Zhong-Tao
author_facet Xia, Dan-Dan
Duan, Hao-Jie
Xie, Fei
Xie, Tian-Peng
Zhang, Yan
Sun, Yue
Lu, Jian-Mei
Gao, Yu-Hong
Zhou, Hao
Ding, Zhong-Tao
author_sort Xia, Dan-Dan
collection PubMed
description Five previously undescribed epoxy octa-hydronaphthalene polyketides, altereporenes A–E (1–5) were isolated from rice culture of the endophytic fungus Alternaria sp. YUD20002 derived from the tubers of Solanum tuberosum. Their structures were determined on the basis of comprehensive spectroscopic analyses, while the absolute configurations were elucidated by the comparison of experimental and calculated specific rotations. Meanwhile, the antimicrobial, cytotoxic, anti-inflammatory and acetylcholinesterase inhibitory activities of compounds 1–5 were also investigated.
format Online
Article
Text
id pubmed-9364171
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-93641712022-08-29 Altereporenes A–E, five epoxy octa-hydronaphthalene polyketides produced by an endophytic fungus Alternaria sp. YUD20002 Xia, Dan-Dan Duan, Hao-Jie Xie, Fei Xie, Tian-Peng Zhang, Yan Sun, Yue Lu, Jian-Mei Gao, Yu-Hong Zhou, Hao Ding, Zhong-Tao RSC Adv Chemistry Five previously undescribed epoxy octa-hydronaphthalene polyketides, altereporenes A–E (1–5) were isolated from rice culture of the endophytic fungus Alternaria sp. YUD20002 derived from the tubers of Solanum tuberosum. Their structures were determined on the basis of comprehensive spectroscopic analyses, while the absolute configurations were elucidated by the comparison of experimental and calculated specific rotations. Meanwhile, the antimicrobial, cytotoxic, anti-inflammatory and acetylcholinesterase inhibitory activities of compounds 1–5 were also investigated. The Royal Society of Chemistry 2022-08-10 /pmc/articles/PMC9364171/ /pubmed/36043060 http://dx.doi.org/10.1039/d2ra03917f Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Xia, Dan-Dan
Duan, Hao-Jie
Xie, Fei
Xie, Tian-Peng
Zhang, Yan
Sun, Yue
Lu, Jian-Mei
Gao, Yu-Hong
Zhou, Hao
Ding, Zhong-Tao
Altereporenes A–E, five epoxy octa-hydronaphthalene polyketides produced by an endophytic fungus Alternaria sp. YUD20002
title Altereporenes A–E, five epoxy octa-hydronaphthalene polyketides produced by an endophytic fungus Alternaria sp. YUD20002
title_full Altereporenes A–E, five epoxy octa-hydronaphthalene polyketides produced by an endophytic fungus Alternaria sp. YUD20002
title_fullStr Altereporenes A–E, five epoxy octa-hydronaphthalene polyketides produced by an endophytic fungus Alternaria sp. YUD20002
title_full_unstemmed Altereporenes A–E, five epoxy octa-hydronaphthalene polyketides produced by an endophytic fungus Alternaria sp. YUD20002
title_short Altereporenes A–E, five epoxy octa-hydronaphthalene polyketides produced by an endophytic fungus Alternaria sp. YUD20002
title_sort altereporenes a–e, five epoxy octa-hydronaphthalene polyketides produced by an endophytic fungus alternaria sp. yud20002
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364171/
https://www.ncbi.nlm.nih.gov/pubmed/36043060
http://dx.doi.org/10.1039/d2ra03917f
work_keys_str_mv AT xiadandan altereporenesaefiveepoxyoctahydronaphthalenepolyketidesproducedbyanendophyticfungusalternariaspyud20002
AT duanhaojie altereporenesaefiveepoxyoctahydronaphthalenepolyketidesproducedbyanendophyticfungusalternariaspyud20002
AT xiefei altereporenesaefiveepoxyoctahydronaphthalenepolyketidesproducedbyanendophyticfungusalternariaspyud20002
AT xietianpeng altereporenesaefiveepoxyoctahydronaphthalenepolyketidesproducedbyanendophyticfungusalternariaspyud20002
AT zhangyan altereporenesaefiveepoxyoctahydronaphthalenepolyketidesproducedbyanendophyticfungusalternariaspyud20002
AT sunyue altereporenesaefiveepoxyoctahydronaphthalenepolyketidesproducedbyanendophyticfungusalternariaspyud20002
AT lujianmei altereporenesaefiveepoxyoctahydronaphthalenepolyketidesproducedbyanendophyticfungusalternariaspyud20002
AT gaoyuhong altereporenesaefiveepoxyoctahydronaphthalenepolyketidesproducedbyanendophyticfungusalternariaspyud20002
AT zhouhao altereporenesaefiveepoxyoctahydronaphthalenepolyketidesproducedbyanendophyticfungusalternariaspyud20002
AT dingzhongtao altereporenesaefiveepoxyoctahydronaphthalenepolyketidesproducedbyanendophyticfungusalternariaspyud20002

Ejemplares similares