Expression of p53 as a biomarker of pazopanib efficacy in solitary fibrous tumours: translational analysis of a phase II trial

BACKGROUND: Solitary fibrous tumours (SFT) are soft tissue sarcomas molecularly defined by the presence of the NAB2::STAT6 intrachromosomal fusion gene. Recently, a prospective phase II trial evaluating the role of the antiangiogenic tyrosine kinase inhibitor pazopanib in SFT has been conducted (NCT...

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Detalles Bibliográficos
Autores principales: Napolitano, Andrea, Moura, David S., Hindi, Nadia, Mondaza-Hernandez, José L, Merino-Garcia, José A., Ramos, Rafael, Dagrada, Gian Paolo, Stacchiotti, Silvia, Graziano, Francesco, Vincenzi, Bruno, Martin-Broto, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364178/
https://www.ncbi.nlm.nih.gov/pubmed/35965642
http://dx.doi.org/10.1177/17588359221116155

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