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The sialodynamic test: A preliminary porcine head study

OBJECTIVES: To provide a concept of measuring pressure changes under constant fluid infusion for the diagnosis of sialolithiasis, termed the sialodynamic test, in a porcine head model. METHODS: Using a porcine head model, a constant infusion of water into the submandibular gland of the two groups ov...

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Autores principales: Dang, Luong Huu, Chen, Yen-Chun, Tseng, How, Su, Chin-Hui, Hung, Shih-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364205/
http://dx.doi.org/10.1177/03000605221115382
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author Dang, Luong Huu
Chen, Yen-Chun
Tseng, How
Su, Chin-Hui
Hung, Shih-Han
author_facet Dang, Luong Huu
Chen, Yen-Chun
Tseng, How
Su, Chin-Hui
Hung, Shih-Han
author_sort Dang, Luong Huu
collection PubMed
description OBJECTIVES: To provide a concept of measuring pressure changes under constant fluid infusion for the diagnosis of sialolithiasis, termed the sialodynamic test, in a porcine head model. METHODS: Using a porcine head model, a constant infusion of water into the submandibular gland of the two groups over 30 s was performed and the outlet pressure was measured. Metal beads were inserted into the salivary duct for obstruction simulation after the normal submandibular gland sialodynamic measurements were completed. Statistical analyses were performed to evaluate the differences between the measured individuals and the experimental group (n = 3). RESULTS: The results showed no significant difference between individuals in the control group, but intergroup variation was noted in the simulated sialolithiasis group. The volume-dependent linear increase in pressure was exacerbated in the simulated sialolithiasis group compared with the control. CONCLUSION: This study indicated that evaluating the relationship between pressure and volume changes can help to determine whether stones are present in the submandibular gland. The sialodynamic test might serve as a potential diagnostic method for salivary diseases.
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spelling pubmed-93642052022-08-11 The sialodynamic test: A preliminary porcine head study Dang, Luong Huu Chen, Yen-Chun Tseng, How Su, Chin-Hui Hung, Shih-Han J Int Med Res Pre-Clinical Research Report OBJECTIVES: To provide a concept of measuring pressure changes under constant fluid infusion for the diagnosis of sialolithiasis, termed the sialodynamic test, in a porcine head model. METHODS: Using a porcine head model, a constant infusion of water into the submandibular gland of the two groups over 30 s was performed and the outlet pressure was measured. Metal beads were inserted into the salivary duct for obstruction simulation after the normal submandibular gland sialodynamic measurements were completed. Statistical analyses were performed to evaluate the differences between the measured individuals and the experimental group (n = 3). RESULTS: The results showed no significant difference between individuals in the control group, but intergroup variation was noted in the simulated sialolithiasis group. The volume-dependent linear increase in pressure was exacerbated in the simulated sialolithiasis group compared with the control. CONCLUSION: This study indicated that evaluating the relationship between pressure and volume changes can help to determine whether stones are present in the submandibular gland. The sialodynamic test might serve as a potential diagnostic method for salivary diseases. SAGE Publications 2022-08-07 /pmc/articles/PMC9364205/ http://dx.doi.org/10.1177/03000605221115382 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Pre-Clinical Research Report
Dang, Luong Huu
Chen, Yen-Chun
Tseng, How
Su, Chin-Hui
Hung, Shih-Han
The sialodynamic test: A preliminary porcine head study
title The sialodynamic test: A preliminary porcine head study
title_full The sialodynamic test: A preliminary porcine head study
title_fullStr The sialodynamic test: A preliminary porcine head study
title_full_unstemmed The sialodynamic test: A preliminary porcine head study
title_short The sialodynamic test: A preliminary porcine head study
title_sort sialodynamic test: a preliminary porcine head study
topic Pre-Clinical Research Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364205/
http://dx.doi.org/10.1177/03000605221115382
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