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Length-dependent poleward flux of sister kinetochore fibers promotes chromosome alignment

Chromosome alignment at the spindle equator promotes proper chromosome segregation and depends on pulling forces exerted at kinetochore fiber tips together with polar ejection forces. However, kinetochore fibers are also subjected to forces driving their poleward flux. Here we introduce a flux-drive...

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Detalles Bibliográficos
Autores principales: Risteski, Patrik, Božan, Domagoj, Jagrić, Mihaela, Bosilj, Agneza, Pavin, Nenad, Tolić, Iva M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364240/
https://www.ncbi.nlm.nih.gov/pubmed/35926461
http://dx.doi.org/10.1016/j.celrep.2022.111169