Cargando…
Length-dependent poleward flux of sister kinetochore fibers promotes chromosome alignment
Chromosome alignment at the spindle equator promotes proper chromosome segregation and depends on pulling forces exerted at kinetochore fiber tips together with polar ejection forces. However, kinetochore fibers are also subjected to forces driving their poleward flux. Here we introduce a flux-drive...
Autores principales: | Risteski, Patrik, Božan, Domagoj, Jagrić, Mihaela, Bosilj, Agneza, Pavin, Nenad, Tolić, Iva M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364240/ https://www.ncbi.nlm.nih.gov/pubmed/35926461 http://dx.doi.org/10.1016/j.celrep.2022.111169 |
Ejemplares similares
-
Microtubule Sliding within the Bridging Fiber Pushes Kinetochore Fibers Apart to Segregate Chromosomes
por: Vukušić, Kruno, et al.
Publicado: (2017) -
Metaphase kinetochore movements are regulated by kinesin-8 motors and microtubule dynamic instability
por: Klemm, Anna H., et al.
Publicado: (2018) -
Bridging the gap between sister kinetochores
por: Tolić, Iva M., et al.
Publicado: (2016) -
Optogenetic control of PRC1 reveals its role in chromosome alignment on the spindle by overlap length-dependent forces
por: Jagrić, Mihaela, et al.
Publicado: (2021) -
Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores
por: Kajtez, Janko, et al.
Publicado: (2016)