Virtual screening and molecular dynamic simulations of the antimalarial derivatives of 2-anilino 4-amino substituted quinazolines docked against a Pf-DHODH protein target

BACKGROUND: The processes of drug development and validation are too expensive to be subjected to experimental trial and errors. Hence, the use of the insilico approach becomes imperative. To this effect, the drug-likeness and pharmacokinetic properties of the ten (10) previously designed derivative...

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Detalles Bibliográficos
Autores principales: Ibrahim, Zakari Ya’u, Uzairu, Adamu, Shallangwa, Gideon Adamu, Abechi, Stephen Eyije, Isyaku, Sulaiman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364290/
https://www.ncbi.nlm.nih.gov/pubmed/37521844
http://dx.doi.org/10.1186/s43042-022-00329-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364290/
https://www.ncbi.nlm.nih.gov/pubmed/37521844
http://dx.doi.org/10.1186/s43042-022-00329-2

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