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Oxa-Michael-based divergent synthesis of artificial glutamate analogs

Herein we report stereoselective generation of two skeletons, 1,3-dioxane and tetrahydropyranol, by oxa-Michael reaction as the key reaction from δ-hydroxyenone. The construction of the 1,3-dioxane skeleton, achieved through hemiacetal formation followed by oxa-Michael reaction from δ-hydroxyenone,...

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Detalles Bibliográficos
Autores principales: Tsukamoto, Shuntaro, Hlokoane, Oriel, Miyako, Kei, Irie, Raku, Sakai, Ryuichi, Oikawa, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364357/
https://www.ncbi.nlm.nih.gov/pubmed/36043066
http://dx.doi.org/10.1039/d2ra03744k