Cargando…

Metabolic profiles of regulatory T cells and their adaptations to the tumor microenvironment: implications for antitumor immunity

Characterized by the expression of the critical transcription factor forkhead box protein P3, regulatory T (Treg) cells are an essential part of the immune system, with a dual effect on the pathogenesis of autoimmune diseases and cancer. Targeting Tregs to reestablish the proinflammatory and immunog...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Yuheng, Huang, Lan, Liu, Yiming, Yi, Ming, Chu, Qian, Jiao, Dechao, Wu, Kongming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364625/ https://www.ncbi.nlm.nih.gov/pubmed/35948909 http://dx.doi.org/10.1186/s13045-022-01322-3

Ejemplares similares

Synergistic effect of immune checkpoint blockade and anti-angiogenesis in cancer treatment
por: Yi, Ming, et al.
Publicado: (2019)

Biological Characteristics and Clinical Significance of Soluble PD-1/PD-L1 and Exosomal PD-L1 in Cancer
por: Niu, Mengke, et al.
Publicado: (2022)

Aging microenvironment and antitumor immunity for geriatric oncology: the landscape and future implications
por: Zhao, Binghao, et al.
Publicado: (2023)

Manipulating Gut Microbiota Composition to Enhance the Therapeutic Effect of Cancer Immunotherapy
por: Yi, Ming, et al.
Publicado: (2019)

Tumor Microenvironment and its Implications for Antitumor Immunity in Cholangiocarcinoma: Future Perspectives for Novel Therapies
por: Cao, Hengsong, et al.
Publicado: (2022)

Tumor immune microenvironment (TIME) to enhance antitumor immunity
por: Rajbhandary, Sajin, et al.
Publicado: (2023)

Synergist for antitumor therapy: Astragalus polysaccharides acting on immune microenvironment
por: Xu, Qian, et al.
Publicado: (2023)

Blocking TGF-β Signaling To Enhance The Efficacy Of Immune Checkpoint Inhibitor
por: Bai, Xianguang, et al.
Publicado: (2019)

Combination of oral STING agonist MSA-2 and anti-TGF-β/PD-L1 bispecific antibody YM101: a novel immune cocktail therapy for non-inflamed tumors
por: Yi, Ming, et al.
Publicado: (2022)

Targeting the tumor microenvironment to enhance antitumor immune responses
por: Van der Jeught, Kevin, et al.
Publicado: (2014)

Senescence Rewires Microenvironment Sensing to Facilitate Antitumor Immunity
por: Chen, Hsuan-An, et al.
Publicado: (2023)

Distinct Roles of VEGFA and ANGPT2 in Lung Adenocarcinoma and Squamous Cell Carcinoma
por: Qin, Shuang, et al.
Publicado: (2020)

Biomarkers for predicting efficacy of PD-1/PD-L1 inhibitors
por: Yi, Ming, et al.
Publicado: (2018)

Effects of tumor metabolic microenvironment on regulatory T cells
por: Wang, Yi-an, et al.
Publicado: (2018)

HDACi promotes inflammatory remodeling of the tumor microenvironment to enhance epitope spreading and antitumor immunity
por: Nguyen, Andrew, et al.
Publicado: (2022)

Regulatory T Cell Metabolism in the Hepatic Microenvironment
por: Wawman, Rebecca Ellen, et al.
Publicado: (2018)

Tumor organoids: applications in cancer modeling and potentials in precision medicine
por: Xu, Hanxiao, et al.
Publicado: (2022)

Tumor Immune Microenvironments (TIMEs): Responsive Nanoplatforms for Antitumor Immunotherapy
por: Sui, Xueqing, et al.
Publicado: (2020)

Immune pressures drive the promoter hypermethylation of neoantigen genes
por: Yi, Ming, et al.
Publicado: (2019)

Iron Metabolism in the Tumor Microenvironment—Implications for Anti-Cancer Immune Response
por: Sacco, Alessandro, et al.
Publicado: (2021)

The Tumor Microenvironment: A Milieu Hindering and Obstructing Antitumor Immune Responses
por: Labani-Motlagh, Alireza, et al.
Publicado: (2020)

Multivalent Carbohydrate Nanocomposites for Tumor Microenvironment Remodeling to Enhance Antitumor Immunity
por: Hyun, Gyu Hwan, et al.
Publicado: (2023)

The Immune Regulatory Role of Adenosine in the Tumor Microenvironment
por: Xing, Jianlei, et al.
Publicado: (2023)

Association of RYR2 Mutation With Tumor Mutation Burden, Prognosis, and Antitumor Immunity in Patients With Esophageal Adenocarcinoma
por: Liu, Zaoqu, et al.
Publicado: (2021)

Meddling with meddlers: curbing regulatory T cells and augmenting antitumor immunity
por: Kochin, Vitaly, et al.
Publicado: (2019)

Development of antitumor biguanides targeting energy metabolism and stress responses in the tumor microenvironment
por: Sakai, Takayuki, et al.
Publicado: (2021)

Immune signature-based risk stratification and prediction of immune checkpoint inhibitor’s efficacy for lung adenocarcinoma
por: Yi, Ming, et al.
Publicado: (2021)

Bridging Innate and Adaptive Antitumor Immunity Targeting Glycans
por: Pashov, Anastas, et al.
Publicado: (2010)

Engaging the Innate and Adaptive Antitumor Immune Response in Lymphoma
por: Csizmar, Clifford M., et al.
Publicado: (2021)

How the Potassium Channel Response of T Lymphocytes to the Tumor Microenvironment Shapes Antitumor Immunity
por: Chirra, Martina, et al.
Publicado: (2022)

Editorial: New insights into antitumor mechanisms based on breast cancer immune microenvironment
por: Yao, Yan, et al.
Publicado: (2023)

Vascular normalization: reshaping the tumor microenvironment and augmenting antitumor immunity for ovarian cancer
por: Yu, Ping, et al.
Publicado: (2023)

Antitumor Therapy Targeting the Tumor Microenvironment
por: Gao, Yuewen, et al.
Publicado: (2023)

Metabolic reprogramming of T regulatory cells in the hypoxic tumor microenvironment
por: Sasidharan Nair, Varun, et al.
Publicado: (2021)

Metabolic Profiling of Inga Species with Antitumor Activity
por: Lima, Nerilson M., et al.
Publicado: (2022)

Optimization of biguanide derivatives as selective antitumor agents blocking adaptive stress responses in the tumor microenvironment
por: Narise, Kosuke, et al.
Publicado: (2014)

Regulatory T Cells: Barriers of Immune Infiltration Into the Tumor Microenvironment
por: Scott, Ellen N., et al.
Publicado: (2021)

Metabolic adaptations of cancer in extreme tumor microenvironments
por: Nakahara, Ryuichi, et al.
Publicado: (2023)

The role of neoantigen in immune checkpoint blockade therapy
por: Yi, Ming, et al.
Publicado: (2018)

Immune Subtypes in LUAD Identify Novel Tumor Microenvironment Profiles With Prognostic and Therapeutic Implications
por: Wang, Feng, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0bsojffjmuab3b5n72kh0v1j34