miR-34a induces neutrophil apoptosis by regulating Cdc42-WASP-Arp2/3 pathway-mediated F-actin remodeling and ROS production

BACKGROUND: The number of neutrophils is significantly reduced in myelodysplastic syndrome (MDS), but the molecular basis remains unclear. We recently found that miR-34a was significantly increased in MDS neutrophils. Therefore, this study aims to clarify the effects of aberrant miR-34a expression o...

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Detalles Bibliográficos
Autores principales: Cao, Meiwan, Peng, Baoling, Chen, Huan, Yang, Min, Chen, Peiyu, Ye, Liping, Wang, Hongli, Ren, Lu, Xie, Jing, Zhu, Jingnan, Xu, Xiangye, Xu, Wanfu, Geng, Lanlan, Gong, Sitang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364709/
https://www.ncbi.nlm.nih.gov/pubmed/35938579
http://dx.doi.org/10.1080/13510002.2022.2102843

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