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All trans-retinoic acid modulates hyperoxia-induced suppression of NF-kB-dependent Wnt signaling in alveolar A549 epithelial cells

INTRODUCTION: Despite recent advances in perinatal medicine, bronchopulmonary dysplasia (BPD) remains the most common complication of preterm birth. Inflammation, the main cause for BPD, results in arrested alveolarization. All trans-retinoic acid (ATRA), the active metabolite of Vitamin A, facilita...

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Detalles Bibliográficos
Autores principales: Tsotakos, Nikolaos, Ahmed, Imtiaz, Umstead, Todd M., Imamura, Yuka, Yau, Eric, Silveyra, Patricia, Chroneos, Zissis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365139/
https://www.ncbi.nlm.nih.gov/pubmed/35947545
http://dx.doi.org/10.1371/journal.pone.0272769

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