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Concentration-dependent transcriptional switching through a collective action of cis-elements

Gene expression specificity of homeobox transcription factors has remained paradoxical. WUSCHEL activates and represses CLAVATA3 transcription at lower and higher concentrations, respectively. We use computational modeling and experimental analysis to investigate the properties of the cis-regulatory...

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Detalles Bibliográficos
Autores principales:	Rodriguez, Kevin, Do, Albert, Senay-Aras, Betul, Perales, Mariano, Alber, Mark, Chen, Weitao, Reddy, G. Venugopala
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365274/ https://www.ncbi.nlm.nih.gov/pubmed/35947668 http://dx.doi.org/10.1126/sciadv.abo6157

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