Neuroinflammation inhibition by small-molecule targeting USP7 noncatalytic domain for neurodegenerative disease therapy

Neuroinflammation is a fundamental contributor to progressive neuronal damage, which arouses a heightened interest in neurodegenerative disease therapy. Ubiquitin-specific protease 7 (USP7) has a crucial role in regulating protein stability in multiple biological processes; however, the potential ro...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Wen, Feng, Na, Liu, Yan-Chen, Guo, Qiang, Wang, Jing-Kang, Bai, Yi-Zhen, Ye, Xiao-Ming, Yang, Zhuo, Yang, Heng, Liu, Yang, Yang, Mi-Mi, Wang, Yan-Hang, Shi, Xiao-Meng, Liu, Dan, Tu, Peng-Fei, Zeng, Ke-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365288/
https://www.ncbi.nlm.nih.gov/pubmed/35947662
http://dx.doi.org/10.1126/sciadv.abo0789

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