A Novel Role for DNA-PK in Metabolism by Regulating Glycolysis in Castration-Resistant Prostate Cancer

PURPOSE: DNA-dependent protein kinase catalytic subunit (DNA-PKcs, herein referred as DNA-PK) is a multifunctional kinase of high cancer relevance. DNA-PK is deregulated in multiple tumor types, including prostate cancer, and is associated with poor outcomes. DNA-PK was previously nominated as a the...

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Detalles Bibliográficos
Autores principales: Dylgjeri, Emanuela, Kothari, Vishal, Shafi, Ayesha A., Semenova, Galina, Gallagher, Peter T., Guan, Yi F., Pang, Angel, Goodwin, Jonathan F., Irani, Swati, McCann, Jennifer J., Mandigo, Amy C., Chand, Saswati, McNair, Christopher M., Vasilevskaya, Irina, Schiewer, Matthew J., Lallas, Costas D., McCue, Peter A., Gomella, Leonard G., Seifert, Erin L., Carroll, Jason S., Butler, Lisa M., Holst, Jeff, Kelly, William K., Knudsen, Karen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365345/
https://www.ncbi.nlm.nih.gov/pubmed/35078861
http://dx.doi.org/10.1158/1078-0432.CCR-21-1846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365345/
https://www.ncbi.nlm.nih.gov/pubmed/35078861
http://dx.doi.org/10.1158/1078-0432.CCR-21-1846

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