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Transcriptomic Profiling of MSI-H/dMMR Gastrointestinal Tumors to Identify Determinants of Responsiveness to Anti–PD-1 Therapy

PURPOSE: Transcriptomic profiling was performed for microsatellite instability-high (MSI-H)/mismatch repair-deficient (dMMR) gastrointestinal tumors to determine the predictors of response to PD-1 blockade. EXPERIMENTAL DESIGN: Thirty-six patients with MSI-H/dMMR gastrointestinal tumors, including g...

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Detalles Bibliográficos
Autores principales:	Chida, Keigo, Kawazoe, Akihito, Suzuki, Toshihiro, Kawazu, Masahito, Ueno, Toshihide, Takenouchi, Kazumasa, Nakamura, Yoshiaki, Kuboki, Yasutoshi, Kotani, Daisuke, Kojima, Takashi, Bando, Hideaki, Mishima, Saori, Kuwata, Takeshi, Sakamoto, Naoya, Watanabe, Jun, Mano, Hiroyuki, Ikeda, Masafumi, Shitara, Kohei, Endo, Itaru, Nakatsura, Tetsuya, Yoshino, Takayuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Translational Cancer Mechanisms and Therapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365358/ https://www.ncbi.nlm.nih.gov/pubmed/35254400 http://dx.doi.org/10.1158/1078-0432.CCR-22-0041

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