Preoperative Chemoradiotherapy plus Nivolumab before Surgery in Patients with Microsatellite Stable and Microsatellite Instability–High Locally Advanced Rectal Cancer

PURPOSE: Preoperative chemoradiotherapy (CRT) and surgical resection are the standard treatment for locally advanced rectal cancer (LARC). Combining immune checkpoint inhibitors with radiation suggests a promising approach for enhancing efficacy. We investigated the efficacy of CRT followed by nivol...

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Detalles Bibliográficos
Autores principales: Bando, Hideaki, Tsukada, Yuichiro, Inamori, Koji, Togashi, Yosuke, Koyama, Shohei, Kotani, Daisuke, Fukuoka, Shota, Yuki, Satoshi, Komatsu, Yoshito, Homma, Shigenori, Taketomi, Akinobu, Uemura, Mamoru, Kato, Takeshi, Fukui, Makoto, Wakabayashi, Masashi, Nakamura, Naoki, Kojima, Motohiro, Kawachi, Hiroshi, Kirsch, Richard, Yoshida, Tsutomu, Suzuki, Yutaka, Sato, Akihiro, Nishikawa, Hiroyoshi, Ito, Masaaki, Yoshino, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Clinical Trials: Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365382/
https://www.ncbi.nlm.nih.gov/pubmed/35063964
http://dx.doi.org/10.1158/1078-0432.CCR-21-3213

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