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Curación de úlcera venosa crónica de la pierna con aloinjerto de membrana amniocoriónica humana fresca

In its fresh state, the amniochorionic membrane contains various multipotential cells, growth factors, and extracellular matrix proteins that contribute to the healing of chronic vascular ulcers. To demonstrate its effectiveness, a fresh human placental membrane allograft was applied to a chronic ve...

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Detalles Bibliográficos
Autores principales: Piamo, Alberto, García, Mayra, Romero, Dayset, Ferrer, Daisy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Nacional de Salud 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365449/
https://www.ncbi.nlm.nih.gov/pubmed/35866726
http://dx.doi.org/10.7705/biomedica.6319
Descripción
Sumario:In its fresh state, the amniochorionic membrane contains various multipotential cells, growth factors, and extracellular matrix proteins that contribute to the healing of chronic vascular ulcers. To demonstrate its effectiveness, a fresh human placental membrane allograft was applied to a chronic venous ulcer in the lower limb of an 89-year-old female patient with a 12 x 10 cm ulcerated lesion of 40 years of evolution in the malleolar area of her left lower limb. Sixty days after the graft, the ulcer was healed in 100% of its surface and a light pink scar on the edges indicated possible pigmentation. Fresh human amniochorionic membrane allograft is a therapeutic alternative for the healing of refractory chronic vascular ulcers of the lower extremities.