Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients

Several mutations that cause Parkinson’s disease (PD) have been identified over the past decade. These account for 15–25% of PD cases; the rest of the cases are considered sporadic. Currently, it is accepted that PD is not a single monolithic disease but rather a constellation of diseases with some...

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Detalles Bibliográficos
Autores principales: Stern, Shani, Lau, Shong, Manole, Andreea, Rosh, Idan, Percia, Menachem Mendel, Ben Ezer, Ran, Shokhirev, Maxim N., Qiu, Fan, Schafer, Simon, Mansour, Abed AlFatah, Mangan, Kile P., Stern, Tchelet, Ofer, Polina, Stern, Yam, Diniz Mendes, Ana Paula, Djamus, Jose, Moore, Lynne Randolph, Nayak, Ritu, Laufer, Sapir Havusha, Aicher, Aidan, Rhee, Amanda, Wong, Thomas L., Nguyen, Thao, Linker, Sara B., Winner, Beate, Freitas, Beatriz C., Jones, Eugenia, Sagi, Irit, Bardy, Cedric, Brice, Alexis, Winkler, Juergen, Marchetto, Maria C., Gage, Fred H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365794/
https://www.ncbi.nlm.nih.gov/pubmed/35948563
http://dx.doi.org/10.1038/s41531-022-00366-z

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