Cargando…

Tumor-derived miR-130b-3p induces cancer-associated fibroblast activation by targeting SPIN90 in luminal A breast cancer

Cancer-associated fibroblasts (CAFs) in the tumor microenvironment (TME) interact closely with cancer cells to promote tumor development. Downregulation of SPIN90 in CAFs has been reported to facilitate breast cancer progression, but the underlying mechanism has not been elucidated. Here, we demonst...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ahn, Suyeon, Kwon, Ahreum, Huh, Yun Hyun, Rhee, Sangmyung, Song, Woo Keun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365846/ https://www.ncbi.nlm.nih.gov/pubmed/35948548 http://dx.doi.org/10.1038/s41389-022-00422-6

Ejemplares similares

Microtubule Acetylation-Specific Inhibitors Induce Cell Death and Mitotic Arrest via JNK/AP-1 Activation in Triple-Negative Breast Cancer Cells
por: Ahn, Suyeon, et al.
Publicado: (2023)

SPIN90, an adaptor protein, alters the proximity between Rab5 and Gapex5 and facilitates Rab5 activation during EGF endocytosis
por: Kim, Hwan, et al.
Publicado: (2019)

SPIN90 Modulates Long-Term Depression and Behavioral Flexibility in the Hippocampus
por: Kim, Dae Hwan, et al.
Publicado: (2017)

SPIN90 Knockdown Attenuates the Formation and Movement of Endosomal Vesicles in the Early Stages of Epidermal Growth Factor Receptor Endocytosis
por: Oh, Hyejin, et al.
Publicado: (2013)

Potent Small-Molecule Inhibitors Targeting Acetylated Microtubules as Anticancer Agents Against Triple-Negative Breast Cancer
por: Kwon, Ahreum, et al.
Publicado: (2020)

The miR-24-3p/p130Cas: a novel axis regulating the migration and invasion of cancer cells
por: Kang, Hoin, et al.
Publicado: (2017)

Author Correction: The miR-24-3p/p130Cas: a novel axis regulating the migration and invasion of cancer cells
por: Kang, Hoin, et al.
Publicado: (2021)

Genetic associations between the miRNA polymorphisms miR-130b (rs373001), miR-200b (rs7549819), and miR-495 (rs2281611) and colorectal cancer susceptibility
por: Kim, Eun-Gyo, et al.
Publicado: (2019)

P21-activated kinase 1: convergence point in PDGF- and LPA-stimulated collagen matrix contraction by human fibroblasts
por: Rhee, Sangmyung, et al.
Publicado: (2006)

Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell
por: Ofori, Jones K., et al.
Publicado: (2017)

NRP1 is targeted by miR-130a and miR-130b, and is associated with multidrug resistance in epithelial ovarian cancer based on integrated gene network analysis
por: CHEN, CHANGXIAN, et al.
Publicado: (2016)

Evaluation of miR‐130 family members as circulating biomarkers for the diagnosis of bladder cancer
por: Wang, Jingyao, et al.
Publicado: (2020)

MiR-221 and miR-130a Regulate Lung Airway and Vascular Development
por: Mujahid, Sana, et al.
Publicado: (2013)

miR-130b duplex (miR-130b-3p/miR-130b-5p) negatively regulates goat intramuscular preadipocyte lipid droplets accumulation by inhibiting Krüppel-like factor 3 expression
por: Li, Yanyan, et al.
Publicado: (2023)

An integrated view of the role of miR-130b/301b miRNA cluster in prostate cancer
por: Fort, Rafael Sebastián, et al.
Publicado: (2018)

Prognostic significance of low DICER expression regulated by miR-130a in cervical cancer
por: He, L, et al.
Publicado: (2014)

SPIN90 Phosphorylation Modulates Spine Structure and Synaptic Function
por: Cho, In Ha, et al.
Publicado: (2013)

Circulating microRNAs miR-331 and miR-195 differentiate local luminal a from metastatic breast cancer
por: McAnena, Peter, et al.
Publicado: (2019)

Clinical Significance of MiR-130b and MiR-125b as Biomarkers in Hepatocellular Carcinoma
por: El-Naidany, Sherin Sobhy, et al.
Publicado: (2022)

Pan-Cancer Analysis of BUB1B/hsa-miR-130a-3p Axis and Identification of Circulating hsa-miR-130a-3p as a Potential Biomarker for Cancer Risk Assessment
por: Ding, Xiaoxia, et al.
Publicado: (2022)

Plasma Levels of miR-27a, miR-130b, and miR-301a in Polycystic Ovary Syndrome
por: Pourteymour Fard Tabrizi, Zahra, et al.
Publicado: (2020)

miR-130a-Mediated KLF3 Can Inhibit the Growth of Lung Cancer Cells
por: Wei, Ming-Chao, et al.
Publicado: (2021)

SPIN90 dephosphorylation is required for cofilin-mediated actin depolymerization in NMDA-stimulated hippocampal neurons
por: Cho, In Ha, et al.
Publicado: (2013)

MiR-130a and MiR-374a Function as Novel Regulators of Cisplatin Resistance in Human Ovarian Cancer A2780 Cells
por: Li, Ningwei, et al.
Publicado: (2015)

Targeting of RUNX3 by miR-130a and miR-495 cooperatively increases cell proliferation and tumor angiogenesis in gastric cancer cells
por: Lee, Sun Hee, et al.
Publicado: (2015)

MiR-100 is a predictor of endocrine responsiveness and prognosis in patients with operable luminal breast cancer
por: Petrelli, Annalisa, et al.
Publicado: (2020)

Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients
por: Qiu, Shuwei, et al.
Publicado: (2013)

Aberrant plasma levels of circulating miR-16, miR-107, miR-130a and miR-146a are associated with lymph node metastasis and receptor status of breast cancer patients
por: Stückrath, Isabel, et al.
Publicado: (2015)

NF-κB-modulated miR-130a targets TNF-α in cervical cancer cells
por: Zhang, Jian, et al.
Publicado: (2014)

CMPK1 Regulated by miR-130b Attenuates Response to 5-FU Treatment in Gastric Cancer
por: Chu, Huaizhu, et al.
Publicado: (2021)

MiR-192, miR-200c and miR-17 are fibroblast-mediated inhibitors of colorectal cancer invasion
por: Ast, Volker, et al.
Publicado: (2018)

Circulating miR‐130b‐ and miR‐21‐based diagnostic markers and therapeutic targets for hepatocellular carcinoma
por: Zhang, Nannan, et al.
Publicado: (2019)

The miR-130a-3p/TGF-βRII Axis Participates in Inhibiting the Differentiation of Fibroblasts Induced by TGF-β1
por: Liu, Yanhong, et al.
Publicado: (2021)

Circular RNA-ZFR Inhibited Cell Proliferation and Promoted Apoptosis in Gastric Cancer by Sponging miR-130a/miR-107 and Modulating PTEN
por: Liu, Tonglei, et al.
Publicado: (2018)

Interleukin-18 and miR-130a in severe sepsis patients with thrombocytopenia
por: Cui, Yao-Li, et al.
Publicado: (2016)

Oncogenic role of MiR-130a in oral squamous cell carcinoma
por: Mallela, Karthik, et al.
Publicado: (2021)

MiR-130b modulates the invasive, migratory, and metastatic behavior of leiomyosarcoma
por: Danielson, Laura S., et al.
Publicado: (2023)

APE1 controls DICER1 expression in NSCLC through miR-33a and miR-130b
por: Antoniali, Giulia, et al.
Publicado: (2022)

Onco-miR-130 promotes cell proliferation and migration by targeting TGFβR2 in gastric cancer
por: Duan, Jingjing, et al.
Publicado: (2016)

Curcumin Suppresses the Colon Cancer Proliferation by Inhibiting Wnt/β-Catenin Pathways via miR-130a
por: Dou, Huiqiang, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_is3q32iebbmebknkjn1ijl2asc