Cargando…

EGFR-mediated activation of adipose tissue macrophages promotes obesity and insulin resistance

Obesity and obesity-related health complications are increasing in prevalence. Adipose tissue from obese subjects has low-grade, chronic inflammation, leading to insulin resistance. Adipose tissue macrophages (ATMs) are a source of proinflammatory cytokines that further aggravate adipocyte dysfuncti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cao, Shirong, Pan, Yu, Tang, Jiaqi, Terker, Andrew S., Arroyo Ornelas, Juan Pablo, Jin, Guan-nan, Wang, Yinqiu, Niu, Aolei, Fan, Xiaofeng, Wang, Suwan, Harris, Raymond C., Zhang, Ming-Zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365849/ https://www.ncbi.nlm.nih.gov/pubmed/35948530 http://dx.doi.org/10.1038/s41467-022-32348-3

Ejemplares similares

Cyclooxygenase-2 in adipose tissue macrophages limits adipose tissue dysfunction in obese mice
por: Pan, Yu, et al.
Publicado: (2022)

Macrophage interferon regulatory factor 4 deletion ameliorates aristolochic acid nephropathy via reduced migration and increased apoptosis
por: Sasaki, Kensuke, et al.
Publicado: (2022)

Epidermal growth factor receptor activation is essential for kidney fibrosis development
por: Cao, Shirong, et al.
Publicado: (2023)

Macrophage Cyclooxygenase-2 Protects Against Development of Diabetic Nephropathy
por: Wang, Xin, et al.
Publicado: (2017)

Kir4.2 mediates proximal potassium effects on glutaminase activity and kidney injury
por: Terker, Andrew S., et al.
Publicado: (2022)

Proximal tubule-derived Colony Stimulating Factor-1 mediates polarization of renal macrophages and dendritic cells, and recovery in acute kidney injury
por: Wang, Yinqiu, et al.
Publicado: (2015)

High sodium intake does not worsen low potassium‐induced kidney damage
por: Zhang, Yahua, et al.
Publicado: (2023)

New Insights into Adipose Tissue Macrophages in Obesity and Insulin Resistance
por: Cai, Zhaohua, et al.
Publicado: (2022)

SBP2 deficiency in adipose tissue macrophages drives insulin resistance in obesity
por: Wang, Ning, et al.
Publicado: (2019)

Netrin-1 promotes adipose tissue macrophage accumulation and insulin resistance in obesity
por: Ramkhelawon, Bhama, et al.
Publicado: (2014)

Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation
por: Shin, Kyung Cheul, et al.
Publicado: (2017)

Staying Connected: Transcriptomics in the Search for Novel Diabetic Kidney Disease Treatments
por: Terker, Andrew S., et al.
Publicado: (2021)

Obesity‐induced insulin resistance and macrophage infiltration of the adipose tissue: A vicious cycle
por: Lee, Chi Ho, et al.
Publicado: (2018)

Role of RAGE in obesity-induced adipose tissue inflammation and insulin resistance
por: Feng, Ziqian, et al.
Publicado: (2021)

Ccrl2 deficiency deteriorates obesity and insulin resistance through increasing adipose tissue macrophages infiltration
por: Xu, Min, et al.
Publicado: (2020)

Subtype-Specific Surface Proteins on Adipose Tissue Macrophages and Their Association to Obesity-Induced Insulin Resistance
por: Strand, Kristina, et al.
Publicado: (2022)

SCAP deficiency facilitates obesity and insulin resistance through shifting adipose tissue macrophage polarization
por: Lee, Jae-Ho, et al.
Publicado: (2022)

Adipose tissue macrophages and their role in obesity-associated insulin resistance: an overview of the complex dynamics at play
por: Guria, Suktara, et al.
Publicado: (2023)

RAGE displays sex-specific differences in obesity-induced adipose tissue insulin resistance
por: Du, Zuoqin, et al.
Publicado: (2022)

Metabolic and Molecular Mechanisms of Macrophage Polarisation and Adipose Tissue Insulin Resistance
por: Orliaguet, Lucie, et al.
Publicado: (2020)

Moderate l-lactate administration suppresses adipose tissue macrophage M1 polarization to alleviate obesity-associated insulin resistance
por: Cai, Hao, et al.
Publicado: (2022)

Macrophage gene expression in adipose tissue is associated with insulin sensitivity and serum lipid levels independent of obesity
por: Ahlin, S, et al.
Publicado: (2013)

Interferon Tau Alleviates Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance by Regulating Macrophage Polarization
por: Ying, Wei, et al.
Publicado: (2014)

Rewiring of Lipid Metabolism in Adipose Tissue Macrophages in Obesity: Impact on Insulin Resistance and Type 2 Diabetes
por: Dahik, Veronica D., et al.
Publicado: (2020)

Adipose Tissue Exosome-Like Vesicles Mediate Activation of Macrophage-Induced Insulin Resistance
por: Deng, Zhong-bin, et al.
Publicado: (2009)

Exenatide improves hepatocyte insulin resistance induced by different regional adipose tissue
por: Bai, Chuanmin, et al.
Publicado: (2022)

Effects of Des-acyl Ghrelin on Insulin Sensitivity and Macrophage Polarization in Adipose Tissue
por: Yuan, Fang, et al.
Publicado: (2021)

Adipose-Derived Stromal Cells Attenuate Adipose Inflammation in Obesity through Adipocyte Browning and Polarization of M2 Macrophages
por: Zhang, Wen-Chao, et al.
Publicado: (2019)

Adipose tissue macrophages: Regulators of adipose tissue immunometabolism during obesity
por: Nance, Sierra A., et al.
Publicado: (2022)

The Roles of Adipokines, Proinflammatory Cytokines, and Adipose Tissue Macrophages in Obesity-Associated Insulin Resistance in Modest Obesity and Early Metabolic Dysfunction
por: Kang, Yea Eun, et al.
Publicado: (2016)

Relationship of obesity to adipose tissue insulin resistance
por: Jiang, Jiajia, et al.
Publicado: (2020)

Corrigendum to “Adipose-Derived Stromal Cells Attenuate Adipose Inflammation in Obesity through Adipocyte Browning and Polarization of M2 Macrophages”
por: Zhang, Wen-Chao, et al.
Publicado: (2022)

Macrophages and Adipocytes in Human Obesity: Adipose Tissue Gene Expression and Insulin Sensitivity During Calorie Restriction and Weight Stabilization
por: Capel, Frédéric, et al.
Publicado: (2009)

Pro-Inflammatory CD11c(+)CD206(+) Adipose Tissue Macrophages Are Associated With Insulin Resistance in Human Obesity
por: Wentworth, John M., et al.
Publicado: (2010)

Improvement of Liquid Fructose-Induced Adipose Tissue Insulin Resistance by Ginger Treatment in Rats Is Associated with Suppression of Adipose Macrophage-Related Proinflammatory Cytokines
por: Wang, Jianwei, et al.
Publicado: (2013)

Organokines and Exosomes: Integrators of Adipose Tissue Macrophage Polarization and Recruitment in Obesity
por: Wang, Yuan-Yuan, et al.
Publicado: (2022)

Increased Macrophage Migration Into Adipose Tissue in Obese Mice
por: Oh, Da Young, et al.
Publicado: (2012)

Macrophage Subsets in Obesity, Aligning the Liver and Adipose Tissue
por: Remmerie, Anneleen, et al.
Publicado: (2020)

Adipose Tissue Macrophage Polarization in Healthy and Unhealthy Obesity
por: Ruggiero, Alistaire D., et al.
Publicado: (2021)

Role of adipose tissue macrophages in obesity-related disorders
por: Chakarov, Svetoslav, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nt1ss03rd4oemf43hke9v5ugkn