Transcriptional dynamics of colorectal cancer risk associated variation at 11q23.1 correlate with tuft cell abundance and marker expression in silico

Colorectal cancer (CRC) is characterised by heritable risk that is not well understood. Heritable, genetic variation at 11q23.1 is associated with increased colorectal cancer (CRC) risk, demonstrating eQTL effects on 3 cis- and 23 trans-eQTL targets. We sought to determine the relationship between 1...

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Detalles Bibliográficos
Autores principales: Harris, Bradley T., Rajasekaran, Vidya, Blackmur, James P., O’Callaghan, Alan, Donnelly, Kevin, Timofeeva, Maria, Vaughan-Shaw, Peter G., Din, Farhat V. N., Dunlop, Malcolm G., Farrington, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365857/
https://www.ncbi.nlm.nih.gov/pubmed/35948568
http://dx.doi.org/10.1038/s41598-022-17887-5

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