Kisspeptin treatment improves fetal-placental development and blocks placental oxidative damage caused by maternal hypothyroidism in an experimental rat model

Maternal hypothyroidism is associated with fetal growth restriction, placental dysfunction, and reduced kisspeptin/Kiss1R at the maternal-fetal interface. Kisspeptin affects trophoblastic migration and has antioxidant and immunomodulatory activities. This study aimed to evaluate the therapeutic pote...

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Detalles Bibliográficos
Autores principales: Santos, Bianca Reis, dos Anjos Cordeiro, Jeane Martinha, Santos, Luciano Cardoso, Barbosa, Erikles Macedo, Mendonça, Letícia Dias, Santos, Emilly Oliveira, de Macedo, Isabella Oliveira, de Lavor, Mário Sergio Lima, Szawka, Raphael Escorsim, Serakides, Rogeria, Silva, Juneo Freitas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365946/
https://www.ncbi.nlm.nih.gov/pubmed/35966095
http://dx.doi.org/10.3389/fendo.2022.908240

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