Insights into the roles of bacterial infection and antibiotics in Parkinson’s disease

Parkinson’s disease (PD) is one of the most common neurodegenerative disorders, which is accompanied with the classical motor symptoms and a range of non-motor symptoms. Bacterial infection affects the neuroinflammation associated with the pathology of PD and various antibiotics have also been confi...

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Autores principales: Sheng, Shuo, Zhao, Shuo, Zhang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366083/
https://www.ncbi.nlm.nih.gov/pubmed/35967873
http://dx.doi.org/10.3389/fcimb.2022.939085
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author Sheng, Shuo
Zhao, Shuo
Zhang, Feng
author_facet Sheng, Shuo
Zhao, Shuo
Zhang, Feng
author_sort Sheng, Shuo
collection PubMed
description Parkinson’s disease (PD) is one of the most common neurodegenerative disorders, which is accompanied with the classical motor symptoms and a range of non-motor symptoms. Bacterial infection affects the neuroinflammation associated with the pathology of PD and various antibiotics have also been confirmed to play an important role not only in bacterial infection, but also in the PD progression. This mini-review summarized the role of common bacterial infection in PD and introduced several antibiotics that had anti-PD effects.
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spelling pubmed-93660832022-08-12 Insights into the roles of bacterial infection and antibiotics in Parkinson’s disease Sheng, Shuo Zhao, Shuo Zhang, Feng Front Cell Infect Microbiol Cellular and Infection Microbiology Parkinson’s disease (PD) is one of the most common neurodegenerative disorders, which is accompanied with the classical motor symptoms and a range of non-motor symptoms. Bacterial infection affects the neuroinflammation associated with the pathology of PD and various antibiotics have also been confirmed to play an important role not only in bacterial infection, but also in the PD progression. This mini-review summarized the role of common bacterial infection in PD and introduced several antibiotics that had anti-PD effects. Frontiers Media S.A. 2022-07-28 /pmc/articles/PMC9366083/ /pubmed/35967873 http://dx.doi.org/10.3389/fcimb.2022.939085 Text en Copyright © 2022 Sheng, Zhao and Zhang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cellular and Infection Microbiology
Sheng, Shuo
Zhao, Shuo
Zhang, Feng
Insights into the roles of bacterial infection and antibiotics in Parkinson’s disease
title Insights into the roles of bacterial infection and antibiotics in Parkinson’s disease
title_full Insights into the roles of bacterial infection and antibiotics in Parkinson’s disease
title_fullStr Insights into the roles of bacterial infection and antibiotics in Parkinson’s disease
title_full_unstemmed Insights into the roles of bacterial infection and antibiotics in Parkinson’s disease
title_short Insights into the roles of bacterial infection and antibiotics in Parkinson’s disease
title_sort insights into the roles of bacterial infection and antibiotics in parkinson’s disease
topic Cellular and Infection Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366083/
https://www.ncbi.nlm.nih.gov/pubmed/35967873
http://dx.doi.org/10.3389/fcimb.2022.939085
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