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Increased frequency of TIGIT+ CD4 T Cell subset in autoantibody-positive first-degree relatives of patients with rheumatoid arthritis
BACKGROUND: Despite immune cell dysregulation being an important event preceding the onset of rheumatoid arthritis (RA), the phenotype of T and B cells in preclinical RA is less understood. The aim of this study was to characterize T and B cell populations in RA patients and their autoantibody (aAb)...
Autores principales: | Anaparti, Vidyanand, Tanner, Stacy, Zhang, Christine, O’Neil, Liam, Smolik, Irene, Meng, Xiaobo, Marshall, Aaron J., El-Gabalawy, Hani |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366176/ https://www.ncbi.nlm.nih.gov/pubmed/35967356 http://dx.doi.org/10.3389/fimmu.2022.932627 |
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