A Phylogeny-aware GWAS Framework to Correct for Heritable Pathogen Effects on Infectious Disease Traits

Infectious diseases are particularly challenging for genome-wide association studies (GWAS) because genetic effects from two organisms (pathogen and host) can influence a trait. Traditional GWAS assume individual samples are independent observations. However, pathogen effects on a trait can be herit...

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Detalles Bibliográficos
Autores principales: Nadeau, Sarah, Thorball, Christian W, Kouyos, Roger, Günthard, Huldrych F, Böni, Jürg, Yerly, Sabine, Perreau, Matthieu, Klimkait, Thomas, Rauch, Andri, Hirsch, Hans H, Cavassini, Matthias, Vernazza, Pietro, Bernasconi, Enos, Fellay, Jacques, Mitov, Venelin, Stadler, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366186/
https://www.ncbi.nlm.nih.gov/pubmed/35921544
http://dx.doi.org/10.1093/molbev/msac163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366186/
https://www.ncbi.nlm.nih.gov/pubmed/35921544
http://dx.doi.org/10.1093/molbev/msac163

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