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Hyperthermia based individual in situ recombinant vaccine enhances lymph nodes drainage for de novo antitumor immunity

The continuing challenges that limit effectiveness of tumor therapeutic vaccines were high heterogeneity of tumor immunogenicity, low bioactivity of antigens, as well as insufficient lymph nodes (LNs) drainage of antigens and adjuvants. Transportation of in situ neoantigens and adjuvants to LNs may...

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Detalles Bibliográficos
Autores principales: Zheng, Cuixia, Liu, Xinxin, Kong, Yueyue, Zhang, Lei, Song, Qingling, Zhao, Hongjuan, Han, Lu, Jiao, Jiannan, Feng, Qianhua, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366229/
https://www.ncbi.nlm.nih.gov/pubmed/35967281
http://dx.doi.org/10.1016/j.apsb.2022.02.026

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