Cargando…

A-kinase interacting protein 1 regulates the cell proliferation, invasion, migration and angiogenesis of clear cell renal cell carcinoma cells and affects the ERK/c-Myc signaling pathway by binding to Rac1

A-kinase interacting protein 1 (AKIP1) has previously been demonstrated to be overexpressed in clear cell renal cell carcinoma (ccRCC) tissues and is associated with patient prognosis. The aim of the present study was to explore whether AKIP1 can affect the proliferation, invasion, migration and ang...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yu, Zhang, Haijian, Han, Zhixing, Wang, Xudong, Li, Xuyu, Yuan, Pengfei, Ji, Shiqi, Liu, Qingjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366277/ https://www.ncbi.nlm.nih.gov/pubmed/35978938 http://dx.doi.org/10.3892/etm.2022.11489

Ejemplares similares

MicroRNA-372 functions as a tumor suppressor in cell invasion, migration and epithelial-mesenchymal transition by targeting ATAD2 in renal cell carcinoma
por: Ji, Shiqi, et al.
Publicado: (2019)

miR-145-5p inhibits the proliferation and migration of bladder cancer cells by targeting TAGLN2
por: Zhang, Haijian, et al.
Publicado: (2018)

Erk1 and Erk2 Regulate Endothelial Cell Proliferation and Migration during Mouse Embryonic Angiogenesis
por: Srinivasan, Ruchika, et al.
Publicado: (2009)

SUMOylation of the GTPase Rac1 is required for optimal cell migration
por: Castillo-Lluva, Sonia, et al.
Publicado: (2010)

Melatonin Suppresses Hypoxia-Induced Migration of HUVECs via Inhibition of ERK/Rac1 Activation
por: Yang, Ling, et al.
Publicado: (2014)

Rac Activation by the T-Cell Receptor Inhibits T Cell Migration
por: Cernuda-Morollón, Eva, et al.
Publicado: (2010)

BMAL1 promotes colorectal cancer cell migration and invasion through ERK‐ and JNK‐dependent c‐Myc expression
por: Shan, Lina, et al.
Publicado: (2022)

The NKD1/Rac1 feedback loop regulates the invasion and migration ability of hepatocarcinoma cells
por: Li, Jie, et al.
Publicado: (2016)

Distinct predictive performance of Rac1 and Cdc42 in cell migration
por: Yamao, Masataka, et al.
Publicado: (2015)

TGF-β-Dependent Growth Arrest and Cell Migration in Benign and Malignant Breast Epithelial Cells Are Antagonistically Controlled by Rac1 and Rac1b
por: Melzer, Catharina, et al.
Publicado: (2017)

Loss of cell–cell adhesion triggers cell migration through Rac1-dependent ROS generation
por: Chen, Yu-Hsuan, et al.
Publicado: (2022)

Rac1 and Rac3 GTPases Regulate the Development of Hilar Mossy Cells by Affecting the Migration of Their Precursors to the Hilus
por: Pennucci, Roberta, et al.
Publicado: (2011)

Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration
por: Marei, Hadir, et al.
Publicado: (2016)

The sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation, and cell migration
por: Saxena, Madhurima, et al.
Publicado: (2013)

Hax-1 is required for Rac1-Cortactin interaction and ovarian carcinoma cell migration
por: Gomathinayagam, Rohini, et al.
Publicado: (2014)

GEP100/Arf6 Is Required for Epidermal Growth Factor-Induced ERK/Rac1 Signaling and Cell Migration in Human Hepatoma HepG2 Cells
por: Hu, ZhenZhen, et al.
Publicado: (2012)

Downregulation of CKS1B restrains the proliferation, migration, invasion and angiogenesis of retinoblastoma cells through the MEK/ERK signaling pathway
por: Zeng, Zhou, et al.
Publicado: (2019)

Metformin targets the GTPase Rac1 to inhibit prostate cancer cell migration
por: Dirat, Béatrice, et al.
Publicado: (2014)

Two Rac1 pools integrate the direction and coordination of collective cell migration
por: Zhou, Sijia, et al.
Publicado: (2022)

Cereblon regulates NK cell cytotoxicity and migration via Rac1 activation
por: Fionda, Cinzia, et al.
Publicado: (2021)

Oncogenic epithelial cell-derived exosomes containing Rac1 and PAK2 induce angiogenesis in recipient endothelial cells
por: Gopal, Shashi K., et al.
Publicado: (2016)

ATIC facilitates cell growth and migration by upregulating Myc expression in lung adenocarcinoma
por: Niu, Niu, et al.
Publicado: (2022)

Suilysin remodels the cytoskeletons of human brain microvascular endothelial cells by activating RhoA and Rac1 GTPase
por: Lv, Qingyu, et al.
Publicado: (2014)

Rac1, caveolin-1 and vascular endothelial growth factor -mediated liver sinusoidal endothelial cell angiogenesis
por: Braet, Filip
Publicado: (2009)

RAC2 acts as a prognostic biomarker and promotes the progression of clear cell renal cell carcinoma
por: Liu, Yuenan, et al.
Publicado: (2019)

Protein Kinase D3 promotes the cell proliferation by activating the ERK1/c‐MYC axis in breast cancer
por: Liu, Yan, et al.
Publicado: (2020)

Role of Activated Rac1/Cdc42 in Mediating Endothelial Cell Proliferation and Tumor Angiogenesis in Breast Cancer
por: Ma, Ji, et al.
Publicado: (2013)

HUWE1 Ubiquitylates and Degrades the RAC Activator TIAM1 Promoting Cell-Cell Adhesion Disassembly, Migration, and Invasion
por: Vaughan, Lynsey, et al.
Publicado: (2014)

Matrix-dependent Tiam1/Rac Signaling in Epithelial Cells Promotes Either Cell–Cell Adhesion or Cell Migration and Is Regulated by Phosphatidylinositol 3-Kinase
por: Sander, Eva E., et al.
Publicado: (1998)

MYADM regulates Rac1 targeting to ordered membranes required for cell spreading and migration
por: Aranda, Juan F., et al.
Publicado: (2011)

Knockdown of RAC1 and VASP gene expression inhibits breast cancer cell migration
por: Tian, Yihao, et al.
Publicado: (2018)

Rac1: A Regulator of Cell Migration and a Potential Target for Cancer Therapy
por: Ma, Ning, et al.
Publicado: (2023)

mTOR Regulation of N-Myc Downstream Regulated 1 (NDRG1) Phosphorylation in Clear Cell Renal Cell Carcinoma
por: Valluri, Anisha, et al.
Publicado: (2023)

Myc-associated zinc-finger protein promotes clear cell renal cell carcinoma progression through transcriptional activation of the MAP2K2-dependent ERK pathway
por: Ren, Li-Xin, et al.
Publicado: (2021)

Inhibition of cell proliferation and migration by Oroxylum indicum extracts on breast cancer cells via Rac1 modulation
por: Buranrat, Benjaporn, et al.
Publicado: (2020)

Correction: Role of Activated Rac1/Cdc42 in Mediating Endothelial Cell Proliferation and Tumor Angiogenesis in Breast Cancer
por: Ma, Ji, et al.
Publicado: (2013)

TNF-α-induced LRG1 promotes angiogenesis and mesenchymal stem cell migration in the subchondral bone during osteoarthritis
por: Wang, Yiyun, et al.
Publicado: (2017)

The Effect of CacyBP/SIP on the Phosphorylation of ERK1/2 and p38 Kinases in Clear Cell Renal Cell Carcinoma
por: Smereczańska, Magdalena, et al.
Publicado: (2023)

Voltage‐dependent activation of Rac1 by Na(v)1.5 channels promotes cell migration
por: Yang, Ming, et al.
Publicado: (2019)

Rab23 promotes squamous cell carcinoma cell migration and invasion via integrin β1/Rac1 pathway
por: Jian, Qiang, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_4o6vnv9b3ps7le48uc2o12g4h5