Cargando…

Ginsenoside Rg1 ameliorates apoptosis, senescence and oxidative stress in ox-LDL-induced vascular endothelial cells via the AMPK/SIRT3/p53 signaling pathway

Coronary heart disease (CHD) mainly refers to coronary atherosclerotic heart disease and its pathogenesis is complex. Ginsenoside Rg1 (Rg1) has a wide range of pharmacological activities, such as antitumor effects, enhancing immunity and exerting protective effects on the vascular system. In the pre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lyu, Tian-Jiao, Zhang, Zi-Xiu, Chen, Jun, Liu, Zong-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366316/ https://www.ncbi.nlm.nih.gov/pubmed/35978936 http://dx.doi.org/10.3892/etm.2022.11482

Ejemplares similares

Ginsenoside Rg1 Ameliorates Pancreatic Injuries via the AMPK/mTOR Pathway in vivo and in vitro
por: Chen, Jin, et al.
Publicado: (2023)

GPR120 Agonist GW9508 Ameliorated Cellular Senescence Induced by ox-LDL
por: Liu, Ruijie, et al.
Publicado: (2020)

Ginsenoside Rg3 Prevents Oxidative Stress-Induced Astrocytic Senescence and Ameliorates Senescence Paracrine Effects on Glioblastoma
por: Hou, Jingang, et al.
Publicado: (2017)

Ginsenoside Rg3 Alleviates ox-LDL Induced Endothelial Dysfunction and Prevents Atherosclerosis in ApoE(−/−) Mice by Regulating PPARγ/FAK Signaling Pathway
por: Geng, Jianan, et al.
Publicado: (2020)

20(S)-ginsenoside Rg3 promotes senescence and apoptosis in gallbladder cancer cells via the p53 pathway
por: Zhang, Fei, et al.
Publicado: (2015)

Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway
por: Ni, Jingyu, et al.
Publicado: (2022)

Activation of Ca(2+)‐AMPK‐mediated autophagy by ginsenoside Rg3 attenuates cellular senescence in human dermal fibroblasts
por: Kim, Dasol, et al.
Publicado: (2021)

Ginsenoside Rg1 Ameliorates Acute Renal Ischemia/Reperfusion Injury via Upregulating AMPKα1 Expression
por: Zhou, Qing, et al.
Publicado: (2022)

Ginsenoside Rg1 ameliorates testicular senescence changes in D-gal-induced aging mice via anti-inflammatory and antioxidative mechanisms
por: Wang, Zi-Ling, et al.
Publicado: (2018)

Metabolism of 20(S)-Ginsenoside Rg(2) by Rat Liver Microsomes: Bioactivation to SIRT1-Activating Metabolites
por: Ma, Li-Yuan, et al.
Publicado: (2016)

20(S)-Ginsenoside Rg2 attenuates myocardial ischemia/reperfusion injury by reducing oxidative stress and inflammation: role of SIRT1
por: Fu, Wenwen, et al.
Publicado: (2018)

20(S)-Ginsenoside Rg3 Promotes Senescence And Apoptosis In Gallbladder Cancer Cells Via The P53 Pathway [Corrigendum]
Publicado: (2019)

A dual Keap1 and p47(phox) inhibitor Ginsenoside Rb1 ameliorates high glucose/ox-LDL-induced endothelial cell injury and atherosclerosis
por: Wang, Zi-Chao, et al.
Publicado: (2022)

Alleviation of diabetic complications by ginsenoside Rg3-enriched red ginseng extract in western diet-fed LDL(–/–) mice
por: Saba, Evelyn, et al.
Publicado: (2018)

PTP1B inhibition ameliorates inflammatory injury and dysfunction in ox-LDL-induced HUVECs by activating the AMPK/SIRT1 signaling pathway via negative regulation of KLF2
por: Zhang, Yunfeng, et al.
Publicado: (2022)

Azilsartan ameliorates ox-LDL-induced endothelial dysfunction via promoting the expression of KLF2
por: Li, Wenfeng, et al.
Publicado: (2021)

Apremilast ameliorates ox-LDL-induced endothelial dysfunction mediated by KLF6
por: Wang, Hao, et al.
Publicado: (2020)

Ginsenoside Rg3 ameliorates allergic airway inflammation and oxidative stress in mice
por: Huang, Wen-Chung, et al.
Publicado: (2021)

Ginsenoside Rg1 ameliorates Alzheimer's disease pathology via restoring mitophagy
por: Wang, Ni, et al.
Publicado: (2023)

Pharmacological activities of ginsenoside Rg5 (Review)
por: Liu, Ming-Yang, et al.
Publicado: (2021)

Ginsenoside Rg1 Regulates SIRT1 to Ameliorate Sepsis-Induced Lung Inflammation and Injury via Inhibiting Endoplasmic Reticulum Stress and Inflammation
por: Wang, Qian-Lu, et al.
Publicado: (2019)

Ginsenoside Rg3 Induces Browning of 3T3-L1 Adipocytes by Activating AMPK Signaling
por: Kim, Kyungtae, et al.
Publicado: (2020)

Effects of Ginsenoside Rg1 Regulating Wnt/β-Catenin Signaling on Neural Stem Cells to Delay Brain Senescence
por: Xiang, Yue, et al.
Publicado: (2019)

Ginsenoside Rg3 Ameliorates Stress of Broiler Chicks Induced by Escherichia coli Lipopolysaccharide
por: Bi, Shicheng, et al.
Publicado: (2022)

SESN1 attenuates the Ox-LDL-induced inflammation, apoptosis and endothelial-mesenchymal transition of human umbilical vein endothelial cells by regulating AMPK/SIRT1/LOX1 signaling
por: Gao, Feng, et al.
Publicado: (2022)

Ginsenoside Rg5 Ameliorates Cisplatin-Induced Nephrotoxicity in Mice through Inhibition of Inflammation, Oxidative Stress, and Apoptosis
por: Li, Wei, et al.
Publicado: (2016)

Baicalein protects against oxLDL-caused oxidative stress and inflammation by modulation of AMPK- alpha
por: Tsai, Kun-Ling, et al.
Publicado: (2016)

Involvement of LDL and ox-LDL in Cancer Development and Its Therapeutical Potential
por: Deng, Chang-Feng, et al.
Publicado: (2022)

Ginsenoside Rg1 Prevents Cognitive Impairment and Hippocampus Senescence in a Rat Model of D-Galactose-Induced Aging
por: Zhu, Jiahong, et al.
Publicado: (2014)

Ginsenoside Rg1 Ameliorates Palmitic Acid-Induced Hepatic Steatosis and Inflammation in HepG2 Cells via the AMPK/NF-κB Pathway
por: Xiao, Qing, et al.
Publicado: (2019)

Ginsenoside Rg1 supplementation clears senescence-associated β-galactosidase in exercising human skeletal muscle
por: Wu, Jinfu, et al.
Publicado: (2019)

Ginsenoside Rg1 ameliorates cardiac oxidative stress and inflammation in streptozotocin-induced diabetic rats
por: Qin, Qiaoji, et al.
Publicado: (2019)

Ginsenoside Rg1 Ameliorates Neuroinflammation via Suppression of Connexin43 Ubiquitination to Attenuate Depression
por: Wang, Huiqin, et al.
Publicado: (2021)

Anti-Angiogenic Properties of Ginsenoside Rg3
por: Nakhjavani, Maryam, et al.
Publicado: (2020)

Comparative Pharmacokinetics of Ginsenoside Rg(3) and Ginsenoside Rh(2) after Oral Administration of Ginsenoside Rg(3) in Normal and Walker 256 Tumor-bearing Rats
por: Fan, He, et al.
Publicado: (2016)

Salvianolic Acid B and Ginsenoside Re Synergistically Protect Against Ox-LDL-Induced Endothelial Apoptosis Through the Antioxidative and Antiinflammatory Mechanisms
por: Yang, Ke, et al.
Publicado: (2018)

Ginsenoside Rg3 attenuates sepsis-induced injury and mitochondrial dysfunction in liver via AMPK-mediated autophagy flux
por: Xing, Wei, et al.
Publicado: (2017)

ASK1 Mediates Apoptosis and Autophagy during oxLDL-CD36 Signaling in Senescent Endothelial Cells
por: Cho, KyoungJoo, et al.
Publicado: (2019)

Resveratrol Enhances Autophagic Flux and Promotes Ox-LDL Degradation in HUVECs via Upregulation of SIRT1
por: Zhang, Yanlin, et al.
Publicado: (2016)

Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway
por: Fan, Xiaodi, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_m2sarrjh441l8o07ebfsua4gps