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Randomized Phase II JANUS Study of Atacicept in Patients With IgA Nephropathy and Persistent Proteinuria

INTRODUCTION: Patients with IgA nephropathy (IgAN) and persistent proteinuria are at risk of progression to kidney failure. Atacicept is a novel B-cell–targeted immunomodulator, shown to reduce immunoglobulin levels in patients with autoimmune diseases. METHODS: JANUS (NCT02808429) was a phase II st...

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Detalles Bibliográficos
Autores principales:	Barratt, Jonathan, Tumlin, James, Suzuki, Yusuke, Kao, Amy, Aydemir, Aida, Pudota, Kishore, Jin, Hulin, Gühring, Hans, Appel, Gerald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Clinical Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366370/ https://www.ncbi.nlm.nih.gov/pubmed/35967104 http://dx.doi.org/10.1016/j.ekir.2022.05.017

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