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Mediastinal melioidosis: A case series from far North Queensland
Melioidosis is the clinical disease caused by the Gram‐negative bacillus Burkholderia pseudomallei and is endemic to Northern Australia and Southeast Asia. It is commonly referred to as the ‘great mimicker’ because of its wide range of clinical presentations, often making diagnosis challenging. Isol...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366404/ https://www.ncbi.nlm.nih.gov/pubmed/35978721 http://dx.doi.org/10.1002/rcr2.1017 |
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author | Gadsby, Bree‐Anna Oaten, Andrew Davies, Phoebe Simpson, Graham Vincent, Stephen |
author_facet | Gadsby, Bree‐Anna Oaten, Andrew Davies, Phoebe Simpson, Graham Vincent, Stephen |
author_sort | Gadsby, Bree‐Anna |
collection | PubMed |
description | Melioidosis is the clinical disease caused by the Gram‐negative bacillus Burkholderia pseudomallei and is endemic to Northern Australia and Southeast Asia. It is commonly referred to as the ‘great mimicker’ because of its wide range of clinical presentations, often making diagnosis challenging. Isolated mediastinal lymphadenopathy as the presenting feature of melioidosis is rare and can be indistinguishable from tuberculosis or malignancy. Endobronchial ultrasound (EBUS) is the preferred technique for evaluating undifferentiated mediastinal lymphadenopathy but its role in the diagnosis of mediastinal melioidosis remains sparsely reported in the literature. In this case series, we present four cases of mediastinal melioidosis, and the role that EBUS guided fine needle aspiration (FNA) played in the diagnosis and management. |
format | Online Article Text |
id | pubmed-9366404 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley & Sons, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-93664042022-08-16 Mediastinal melioidosis: A case series from far North Queensland Gadsby, Bree‐Anna Oaten, Andrew Davies, Phoebe Simpson, Graham Vincent, Stephen Respirol Case Rep Case Series Melioidosis is the clinical disease caused by the Gram‐negative bacillus Burkholderia pseudomallei and is endemic to Northern Australia and Southeast Asia. It is commonly referred to as the ‘great mimicker’ because of its wide range of clinical presentations, often making diagnosis challenging. Isolated mediastinal lymphadenopathy as the presenting feature of melioidosis is rare and can be indistinguishable from tuberculosis or malignancy. Endobronchial ultrasound (EBUS) is the preferred technique for evaluating undifferentiated mediastinal lymphadenopathy but its role in the diagnosis of mediastinal melioidosis remains sparsely reported in the literature. In this case series, we present four cases of mediastinal melioidosis, and the role that EBUS guided fine needle aspiration (FNA) played in the diagnosis and management. John Wiley & Sons, Ltd 2022-08-11 /pmc/articles/PMC9366404/ /pubmed/35978721 http://dx.doi.org/10.1002/rcr2.1017 Text en © 2022 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Series Gadsby, Bree‐Anna Oaten, Andrew Davies, Phoebe Simpson, Graham Vincent, Stephen Mediastinal melioidosis: A case series from far North Queensland |
title | Mediastinal melioidosis: A case series from far North Queensland
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title_full | Mediastinal melioidosis: A case series from far North Queensland
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title_fullStr | Mediastinal melioidosis: A case series from far North Queensland
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title_full_unstemmed | Mediastinal melioidosis: A case series from far North Queensland
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title_short | Mediastinal melioidosis: A case series from far North Queensland
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title_sort | mediastinal melioidosis: a case series from far north queensland |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366404/ https://www.ncbi.nlm.nih.gov/pubmed/35978721 http://dx.doi.org/10.1002/rcr2.1017 |
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